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( Mark One ) ☐ 図 ☐ ☐ As filed with the Securities and Exchange Commission on April 15 , 2021 . UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON , D.C. 20549 FORM 20 - F REGISTRATION STATEMENT PURSUANT TO SECTION 12 ( b ) OR ( g ) OF THE SECURITIES EXCHANGE ACT OF 1934 OR ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31 , 2020 OR TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to OR SHELL COMPANY REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of event requiring this shell company report For the transition period from to Commission file number 001-39670 PURETECH HEALTH PLC ( Exact name of registrant as specified in its charter ) N / A ( Translation of Registrant's name into English ) England and Wales ( Jurisdiction of incorporation or organization ) 6 Tide Street , Suite 400 Boston , Massachusetts 02210 United States ( Address of principal executive offices ) Daphne Zohar Chief Executive Officer Tel : ( 617 ) 482-2333 ( Name , telephone , e - mail and / or facsimile number and address of company contact person ) Securities registered or to be registered pursuant to Section 12 ( b ) of the Act :