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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D.C. 20549 FORM 10 - K ( Mark One ) X ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31 , 2020 OR TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Florida ( State or other jurisdiction of incorporation or organization ) Commission file number 1-13165 CRYOLIFE , INC . ( Exact name of registrant as specified in its charter ) Title of each class Common Stock , $ .01 par value Securities registered pursuant to Section 12 ( g ) of the Act : None Large accelerated filer x Non - accelerated filer o 59-2417093 1655 Roberts Boulevard N.W. , Kennesaw , GA 30144 ( Address of principal executive offices ) ( zip code ) Registrant's telephone number , including area code ( 770 ) 419-3355 Securities registered pursuant to Section 12 ( b ) of the Act : Trading Symbol ( s ) CRY ( I.R.S. Employer Identification No. ) Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Yes x No o Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15 ( d ) of the Act . Yes o No x Indicate by check mark whether the registrant ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange ct 1934 during the preceding 12 mont ( or suc hort period that the registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes x No o Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( § 232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the registrant was required to submit such files ) . Yes x No Name of each exchange on which registered New York Stock Exchange Indicate by check mark whether the registrant is a large accelerated filer , an accelerated filer , a non - accelerated filer , a smaller reporting company , or emerging growth company . See definitions of " large accelerated filer ” , “ accelerated filer ” , “ smaller reporting company " , and " emerging growth company " in Rule 12b - 2 of the Exchange Act . ( Check one ) . Accelerated filer o Smaller reporting company o Emerging growth company o If an emerging growth company , indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13 ( a ) of the Exchange Act . ¨ Indicate by check mark whether the registrant has filed a report on and attestation to its management's assessment of the effectiveness of its internal control over financial reporting under Section 404 ( b ) of the Sarbanes - Oxley Act ( 15 U.S.C. 7262 ( b ) ) by the registered public accounting firm that prepared or issued its audit report . x Indicate by check mark whether the registrant is a shell company ( as defined in Rule 12b - 2 of the Exchange Act ) . Yes o No x Document Proxy Statement for the Annual Meeting of Stockholders to be filed within 120 days after December 31 , 2020 As of June 30 , 2020 the aggregate market value of the voting stock of the Registrant held by non - affiliates of the registrant was $ 694,069,423 computed using the closing price of $ 19.17 per share of Common Stock on June 30 , 2020 , the last trading day of the registrant's most recently completed second fiscal quarter , as reported by the New York Stock Exchange , based on management's belief that Registrant has no affiliates other than its directors and executive officers . As of February 12 , 2021 the number of outstanding shares of Common Stock of the registrant was 38,956,550 . Documents Incorporated By Reference Parts Into Which Incorporated Part III