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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D.C. 20549 FORM 10 - K ( Mark One ) ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31 , 2020 OR TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM ΤΟ Commission File Number 001-39659 Biodesix , Inc. ( Exact name of Registrant as specified in its Charter ) Delaware ( State or other jurisdiction of incorporation or organization ) 2970 Wilderness Place , Suite 100 Boulder , CO ( Address of principal executive offices ) Securities registered pursuant to Section 12 ( b ) of the Act : 80301 ( Zip Code ) Registrant's telephone number , including area code : ( 303 ) 417-0500 U 20-3986492 ( I.R.S. Employer Identification No. ) Trading Symbol ( s ) BDSX Title of each class Common Stock , par value $ 0.001 per share Securities registered pursuant to Section 12 ( g ) of the Act : None Indicate by check mark if the Registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . YES NO > Indicate by check mark if the Registrant is not required to file reports pursuant to Section 13 or 15 ( d ) of the Act . YES NO Indicate by check mark whether the Registrant : ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months ( or for such shorter period that the Registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . YES > NO Name of each exchange on which registered The NASDAQ Global Market Indicate by check mark whether the Registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( §232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the Registrant was required to submit such files ) . YES NO Indicate by check mark whether the registrant is a large accelerated filer , an accelerated filer , a non - accelerated filer , smaller reporting company , or an emerging growth company . See the definitions of " large accelerated filer , " " accelerated filer , " " smaller reporting company , " and " emerging growth company " in Rule 12b - 2 of the Exchange Act . Large accelerated filer Non - accelerated filer Emerging growth company If an emerging growth company , indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13 ( a ) of the Exchange Act . □ Accelerated filer Smaller reporting company Indicate by check mark whether the registrant has filed a report on and attestation to its management's assessment of the effectiveness of its internal control over financial reporting under Section 404 ( b ) of the Sarbanes - Oxley Act ( 15 U.S.C. 7262 ( b ) ) by the registered public accounting firm that prepared or issued its audit report . Indicate by check mark whether the Registrant is a shell company ( as defined in Rule 12b - 2 of the Exchange Act ) . YES NO The aggregate market value of the Registrant's common stock , par value $ .001 per share ( the " Common Stock " ) held by non - affiliates was approximately $ 344,635,079 based upon the December 31 , 2020 , closing price of $ 20.16 as reported by the Nasdaq Global Select Market . The Registrant has elected to use December 31 , 2020 as the calculation date , which was the last trading date of the registrant's most recently completed fiscal year , because on June 30 , 2020 ( the last business day of the registrant's second fiscal quarter ) , the Registrant was a privately held company . The number of shares of Registrant's Common Stock outstanding as of March 12 , 2021 was 26,577,782 . DOCUMENTS INCORPORATED BY REFERENCE Portions of the Company's definitive Proxy Statement for its 2021 Annual Meeting Sh eholders are to be incorporated by reference into Part III , as specifically set forth in Part III . )