Good day, and welcome to the Bionano first quarter 2024 earnings conference call. Today's conference is being recorded. At this time, I would like to turn the conference over to David Holmes from Investor Relations. Please go ahead. Thank you, operator, and good afternoon, everyone. Welcome to the Bionano first quarter 2024 financial results conference call. Leading the call today is Dr. Erik Holmlin, CEO of Bionano. He is joined by Gülsen Kama, CFO of Bionano. After market close today, Bionano issued a press release announcing its financial results for the first quarter, 2024. A copy of the release can be found on the investor relations page of the company's website. Certain statements made during the conference call may be forward-looking statements, including statements about Bionano's revenue outlook, profitability, cash runway, cost savings initiatives, and commercialization and product plans. Such statements are based on current expectations, and there can be no assurances that the results contemplated in these statements will be realized. Actual results may differ materially from such statements due to a number of factors and risks, some of which are identified in Bionano's press release and Bionano's reports filed with the SEC. These forward-looking statements are based on information available to Bionano today, May 8th, 2024, and the company assumes no obligation to update statements as circumstances change. In addition, to supplement Bionano's financial results reported in accordance with the U.S. generally accepted accounting principles, or GAAP, the company reports certain non-GAAP financial measures. A description of these non-GAAP financial measures, as well as a reconciliation to the nearest GAAP financial measures, are included at the end of the company's earnings release issued earlier today, which has been posted on the investor relations page of the company's website. These non-GAAP financial measures are not meant to be considered in isolation or as a substitute for comparable GAAP measures, should be read in conjunction with the company's consolidated financial statements prepared in accordance with GAAP, have no standardized meaning prescribed by GAAP, and are not prepared under any comprehensive set of accounting rules or principles. An audio recording and webcast replay for today's conference call will also be available online on the company's investor relations page. With that, I will turn the call over to Erik. Thank you, David, and good afternoon, everyone. We accomplished a lot in Q1, and I look forward to discussing the progress in detail. I want to start off today's call, however, by sharing a remarkable story of medical advancement in which optical genome mapping played a significant role. I'm referring to the first successful kidney transplant from a genetically modified pig into a human patient, which was conducted at Massachusetts General Hospital on March 16th. eGenesis, a Bionano customer and OGM user, provided the kidney from a pig donor that was genetically edited using CRISPR-Cas9 technology to remove harmful pig genes and add certain human genes to improve its compatibility with humans. They also used gene editing to inactivate porcine endogenous retroviruses in the pig donor to eliminate any risk of infection in humans. The process of creating the cells that eventually grew into the pig donor followed multiple steps of genetic modification to eventually arrive at the cells that were used to grow the donor. Throughout the process, Optical Genome Mapping was used as part of a regimen to confirm that desired gene edits were in place, and that off-target effects were not detected, or those that were detected were not deleterious. Optical Genome Mapping was used as an alternative to G-banding karyotype analysis because of its ability to detect genome variation that other methods commonly miss. We are seeing growth in our biopharma customer group, and we believe it's because these customers see tremendous value in OGM's utility for the development of safe and innovative therapies. Our focus in 2024 remains on strengthening the company's long-term growth profile. As part of our ongoing evolution, we are continuing to execute cost savings and strategic productivity initiatives that we began in May of 2023, and that are intended to allow us to be more agile, to increase efficiency across the company, and to prioritize investing in opportunities where we see the greatest potential to drive adoption and utilization of optical genome mapping across multiple end markets. Gülsen is going to open our call today by walking you through our financial results for the quarter and explaining how some of the steps in our streamlined operational plan have begun to positively impact our financial performance and cash runway. Gülsen? Thanks, Erik. With that, let me share our results for the first quarter of 2024 with you. Revenue was $8.8 million, representing an 18% year-over-year increase compared to the same period of 2023. Excluding $1.4 million in revenues from discontinued clinical services in the first quarter of 2024. Core revenues were $7.3 million, which represents a 21% year-over-year growth over the $6.1 million of core revenues for the same period in 2023. The OGM installed base grew to 347 systems during Q1, which represents an increase of 21 systems during the quarter and 34% growth over the installed base of 259 at the end of Q1, 2023. We sold 8,249 flow cells in Q1 2024, which represents a 58% year-over-year increase over the 5,226 flow cells sold in the same period last year. GAAP gross margin for the first quarter was 32%, compared to 28% during Q1 2023, and non-GAAP gross margin was 34%, compared to 30% in the same quarter last year. First quarter 2024 non-GAAP gross margin excludes $128,000 in stock-based compensation and $11,000 of restructuring expense. First quarter 2024 GAAP operating expense was $33.9 million, and non-GAAP operating expense was $24.7 million. Non-GAAP operating expense in the quarter excludes restructuring costs, stock-based compensation, and other adjustments, as detailed in the reconciliation table accompanying the press release posted on the investor relations page of our website. In the same period in 2023, GAAP operating expense was $39.9 million, and non-GAAP operating expense was $33.6 million. Q1 2023 GAAP to non-GAAP reconciliation can be found in the same table. Our cash, cash equivalents, and available-for-sale securities as of March 31st, 2024, were $53.2 million, compared to cash, cash equivalents, and available-for-sale securities of $102.3 million as of December 31st, 2023. As of March 31st, 2024, $24.8 million was subject to certain restrictions, compared to $35.5 million as of December 31, 2023. We raised $15.1 million in net proceeds in the first quarter of 2024 through our ATM facility. The change in total cash balance from December 31st, 2023, to March 31st, 2024, consists of $19 million cash burn from operating activities, excluding interest and debt retirement fees, $9 million in interest and debt retirement fees, $37 million in repaid principal, offset by $15 million in net ATM proceeds. Now, I want to discuss the steps we have taken to continue to streamline operations, reduce expenses, and to extend our cash runway. The non-GAAP operating expenses in the quarter are consistent with our planned reductions announced in October 2023. In March, we expanded those initiatives to include further reduction in force and reductions to discretionary spending unrelated to headcount. Overall, since May 2023 through Q2 of 2024, we plan to have reduced headcount by over 200 people. Compared to the annualized non-GAAP operating expense for the first quarter of 2023, these initiatives are expected to reduce annualized non-GAAP operating expenses by about $65million-$75 million by Q1 of 2025. We also announced a registered direct offering priced at the market under Nasdaq rules in April 2024, with gross proceeds to the company of approximately $10 million, before deducting the placement agent's fees and other offering expenses payable by the company. We believe these activities will allow us to remain committed to our customers and partners, and to be able to continue expanding the opportunity and availability of OGM. Back to you, Erik. Thanks, Gülsen. Our strategy moving forward is straightforward. We need to continue to accelerate revenue growth, operate efficiently, and raise capital that will allow us to extend our cash runway on a path to profitability. Key updates to our product portfolio, which we believe will drive this growth, include the Stratys system, which is now fully commercially available, and early feedback by adopters has been positive. We're shipping commercial production units now, and we have the capacity to meet the expected demand. We expect to announce later this week a series of major advancements to our entire suite of comprehensive analysis software tools for cancer, including version 7.1 of our VIA software, which has AI-enhanced capabilities for cancer research. In the second half of the year, we plan to release improvements to the data analysis processing time on the Stratys Compute, which is a high-performance workstation developed in collaboration with NVIDIA. We are addressing the DNA isolation bottleneck with isotachophoresis technology on the Ionic system, which was acquired in our acquisition of Purigen Biosystems. We placed a pre-commercial system in the field for optical genome mapping on the Ionic system, using a newly developed ITP cartridge for the isolation of ultra-high molecular weight DNA in the fourth quarter of 2023, and we have recently added two more customer sites. We are on track for a full commercial release of the product in the third quarter of 2024. Now, the objective in assembling this combination of solutions, high throughput data collection with Stratys, streamlined analysis and reporting with VIA, and automated DNA isolation with Ionic, is to enable optical genome mapping at scale for routine use. We're pleased to announce and congratulate Dr. Alexander Hoischen and his team at Radboud University Medical Center in the Netherlands on their award by the Research and Innovation Board at Radboud UMC, of a grant of EUR 900,000 for the translation of optical genome mapping to routine use in an academic medical center, where they will focus on leukemias, solid tumors, and constitutional genetic diseases. This work will leverage our high throughput end-to-end workflow. On progress in market development, the first quarter in 2024 saw the highest number of optical genome mapping publications in any quarter in our history. 97 total publications, which is up 83% compared to the number of publications in the first quarter of 2023. Growth in publications has an influence on how all stakeholders view optical genome mapping, from prospective customers to third-party payers and medical societies, so this growth is really outstanding. Our clinical studies are now streamlined based on our cost savings initiatives, and they are focused primarily on advancing the Heme trial, while publishing more pre and postnatal study data from the constitutional trials. Finally, I'd like to comment briefly on an application that has been submitted to the American Medical Association for a category one CPT code, covering optical genome mapping. We understand that the application may be reviewed at the CPT editorial panel meeting, which starts tomorrow, May 9th, at 9:00 A.M. Eastern Time. This application is the third one that's been submitted for optical genome mapping, but in the previous two cycles, it was withdrawn prior to the editorial panel meeting. We view the fact that it will go now in front of that panel as a sign of progress, and we are eagerly awaiting the outcome, which will be published publicly on or before June 6th. Although, we do understand that the meeting taking place will be public, and it's possible that anyone who registers may be able to attend. A link to register for this meeting is listed on the American Medical Association website. Looking ahead, we remain on track to meet our goal of installing 381-401 OGM systems by the end of 2024, which reflects some anticipated Saphyr to Stratys upgrades. We expect Q2 revenue guidance to be in the range of $7.8 million-$8.2 million, and we are maintaining our full year 2024 revenue guidance of $37 million-$41 million. Keep in mind that both of these ranges take into account the financial impact of discontinuing certain clinical services products as part of our cost reduction initiatives. In closing, I'm excited about the progress we have made in 2024. We acknowledge challenges we are facing due to the current state of capital markets, and we need to continue the great momentum we have built. I am confident in optical genome mapping's ability to transform the field of cytogenetics. And with that, operator, please go ahead and open the line for questions. Thank you. Ladies and gentlemen, we will now begin the question-and-answer session. To ask a question, you may press star, then one on your telephone keypad. If you're using a speakerphone, please pick up your handset before pressing the keys. To withdraw your question, please press star, then two. Again, press star, then one to ask a question. At this time, we will pause momentarily to assemble our roster. The first question will be from Sung Ji Nam from Scotiabank. Please go ahead. Hi, thanks for taking the question. Was curious if there were any Stratys placements in the first quarter or upgrades from Saphyr to Stratys in the first quarter? And then, Erik, you talked about the capital spending constraints. You know, if you're seeing kind of the split between instrument sales versus reagent rentals, if you see that ticking up onto, you know, towards the reagent rental side in the current environment. Yeah. Thanks, Sung Ji. So I think all of us in the space are feeling constraints around available funding. In our quarter, reagent rentals edged out capital sales, but I think that's just kind of within the normal ranges of what we would expect. It is, it is slightly elevated. That's a very attractive vehicle to bring a system in. And, you know, it's something that we're paying attention to going forward. But I don't think we've felt that pressure, and the reason is that optical genome mapping is something which is really new and unique, and the deals that are getting done, for example, in that first quarter and now, in this second quarter, have been in the works for a while. And so we might see something creeping in perhaps later in the year, as a result of that current environment. But we're being mindful of it, and we recognize that, you know, our peers are definitely seeing it. With regard to Stratys uptake during the quarter, yes, we had several successful programs that involved Stratys. And for the time being, we're not really breaking out Stratys from the overall total number of growth of OGM systems in the space, and we'll see how important it is to do that going forward. But, you know, for right now, we're not breaking it out, but the progress continues to be solid. And just anecdotally, I don't think we've seen a conversion yet. There are several of them that are in discussions. You know, so we expect that to probably be something that would, you know, drive some of the numbers and the dynamics of the installed base growth going forward. But anecdotally, I don't think we've seen a conversion yet. It's all been incremental addition of Stratys, either to an existing customer or to a new customer. Gotcha, that's helpful. And then just on the Ionic purification system, great to see, nice traction there from the early access site. Just curious, how should we think about the potential ramp of that platform? Do you expect that to go to-- do you expect the early adopters to be kind of the Stratys customers purchasing Stratys systems as well? Or do you anticipate a significant portion of your existing Saphyr customers to also adopt? And also, could this be used outside of OGM applications? Yeah, let me take the last question first. So the Ionic system has been available for a couple of years now, and we've actually, even during the time that we've had that technology in-house after the acquisition of Purigen Biosystems, have gone through a kind of an upgrade cycle, not of the instrument, but of the reagents and consumables that are used. And the applications are for nucleic acid isolation, DNA and RNA, from a variety of sample types. But the majority of uptake and utilization is for formalin-fixed, paraffin-embedded, or FFPE samples. And customers are using that for nucleic acid isolation prior to sequencing, and they like isotachophoresis because it produces really pure sample, much cleaner than they get off of typical column-based methods. So this is something that we see as a very interesting product for us and a source of revenues going forward. We're not able, just in the current cost-constrained environment, to really put you know, direct, dedicated salespeople on it, but we do offer it independently of OGM as part of what our sales reps are offering to customers. Now, with regard to the adoption that we're expecting around optical genome mapping, generally speaking, we expect to see adoption by the higher volume routine users, and those would include Saphyr existing sites. We have quite a number of sites that are running you know, hundreds of samples per year, and so they would benefit from integrating the Ionic system into their workflows. But we also expect Stratys users to be the more obvious adopters of isotachophoresis. Some of the reasons are that in one cartridge with isotachophoresis, we expect you'll be able to run, you know, eight samples for ultra-high molecular weight DNA isolation, and the process itself is completed in a matter of hours. Now, it takes overnight for the nucleic acid to be ready to be labeled and then imaged, but the actual isotachophoresis process itself is incredibly rapid. And so I think what you're gonna see is that the higher volume users are going to adopt it, and, you know, those are the ones that are driving consumables purchases now and will be the future. Great. Thank you. We'll get back in the queue. Thanks, Sung Ji. Thank you. Again, if you would like to ask a question, please press star, then one. Again, pressing star then one will allow you to ask a question. Ladies and gentlemen, showing no further questions, this concludes our question and answer session. I will turn the conference back over to Dr. Erik Holmlin for any closing remarks. Oh, thank you very much, operator. I want to thank everybody for joining, and we are looking forward to updating you on our progress on our Q2 call. Have a great day. Thank you very much. The conference has now concluded. Thank you for attending today's presentation. You may now disconnect.