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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D.C. 20549 FORM 10 - K FOR ANNUAL AND TRANSITION REPORTS PURSUANT TO SECTIONS 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 ( Mark One ) X ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31 , 2020 OR TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to 001-38807 ( Commission file number ) ANCHIANO THERAPEUTICS LTD . ( Exact name of registrant as specified in its charter ) Israel ( State or other jurisdiction of incorporation or organization ) One Kendall Square Building 1400E Suite 14-105 Cambridge , MA ( Address of principal executive offices ) 81-3676773 ( I.R.S. Employer Identification No. ) 02139 ( Zip Code ) ( 857 ) 259-4622 Registrant's telephone number , including area code Securities registered pursuant to Section 12 ( b ) of the Act : Title of each class American Depositary Shares , each representing five ordinary shares , no par value per share Ordinary shares , no par value per share Trading Symbol ( s ) ANCN n / a Name of each exchange on which registered Nasdaq Capital Market Nasdaq Capital Market * * Not for trading ; only in connection with the registration of American Depositary Shares . Securities registered pursuant to Section 12 ( g ) of the Act : None Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Yes Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15 ( d ) of the Act . Yes No x No x Indicate by check mark whether the registrant ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months ( or for such shorter period that the registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes x No " Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( §232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the registrant was required to submit such files ) . Yes x No¨