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Table of Contents ☐ ☑ ☐ UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D.C. 20549 Form 20 - F REGISTRATION STATEMENT PURSUANT TO SECTION 12 ( b ) or 12 ( g ) OF THE SECURITIES EXCHANGE ACT OF 1934 OR ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31 , 2020 OR TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 OR □ SHELL COMPANY REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES Exchange ACT OF 1934 Commission File Number : 001-39522 COMPASS Pathways plc ( Exact name of registrant as specified in its charter ) England and Wales ( Jurisdiction of Incorporation ) 3rd Floor 1 Ashley Road Altrincham Cheshire WA14 2DT United Kingdom Tel : +1 ( 646 ) 905-3974 ( Address of principal executive offices ) Nate Poulsen COMPASS Pathways plc 180 Varick Street New York , New York 10014 Tel : +1 ( 646 ) 905-3974 ( Name , telephone , e - mail and / or facsimile number and address of Company contact person ) Securities registered or to be registered , pursuant to Section 12 ( b ) of the Act Title of Each Class American Depositary Shares , each representing one ordinary share , par value of £ 0.008 per share Ordinary shares , par value of £ 0.008 per share * * Not for trading , but only in connection with registration of American Depositary Shares . Trading Symbol CMPS CMPS Name of each exchange on which registered Nasdaq Global Select Market Nasdaq Global Select Market * Securities registered or to be registered pursuant to Section 12 ( g ) of the Act : None Securities for which there is a reporting obligation pursuant to Section 15 ( d ) of the Act : None Indicate the number of outstanding shares of each of the issuer's classes of capital or common stock as of the close of the period covered by the annual report : 35,930,331 Ordinary Shares , par value £ 0.008 per share . Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Yes ☐ No ☑ If this report is an annual or transition report , indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or 15 ( d ) of the Securities Exchange Act of 1934. Yes ☐ No ☑ Indicate by check mark whether the registrant ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months ( or for such shorter period that the registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes > No ☐ Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( § 232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the registrant was required to submit such files ) . Yes > No □ Indicate by check mark whether the registrant is a large accelerated filer , an accelerated filer , a non - accelerated filer , or an emerging growth company . See the definitions of " large accelerated filer , " " accelerated filer , " and " emerging growth company " in Rule 12b - 2 of the Exchange Act . Large accelerated filer ☐ Accelerated filer ☐ Emerging growth company ☑ Non - accelerated filer ☑