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UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON , DC 20549 ( Mark One ) ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from Commission file number : 001-35867 Delaware ( State or Other Jurisdiction of Incorporation or Organization ) Form 10 - K Title of each class Common Stock , par value $ 0.001 per For the fiscal year ended December 31 , 2020 or 2505 Meridian Parkway , Suite 100 Durham , North Carolina ( Address of Principal Executive Offices ) Chimerix , Inc. ( Exact Name of Registrant as Specified in its Charter ) share to ( 919 ) 806-1074 ( Registrant's Telephone Number , Including Area Code ) Securities registered pursuant to Section 12 ( b ) of the Act : Trading Symbol ( s ) CMRX 33-0903395 ( I.R.S. Employer Identification No. ) 27713 ( Zip Code ) Name of each exchange on which registered The Nasdaq Global Market Securities registered pursuant to Section 12 ( g ) of the Act : None No ο Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Yes x No X Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or 15 ( d ) of the Act . Yes o Indicate by check mark whether the registrant : ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months ( or for such shorter period that the registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes x No ο Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( §232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the registrant was required to submit such files ) . Yes x No o Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S - K is not contained herein , and will not be contained , to the best of the registrant's knowledge , in definitive proxy or information statements incorporated by reference in Part III of this Form 10 - K or any amendment to this Form 10 - K . X