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Table of Contents ( Mark One ) ANNUAL REPORT PURSUANT TO SECTION 13 or 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31 , 2020 or ☐ UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D. C. 20549 FORM 10 - K TRANSITION REPORT PURSUANT TO SECTION 13 or 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission file number 001-36792 Delaware ( State or other jurisdiction of incorporation or organization ) Title of each class : Common Stock , $ 0.001 par value CYTOSORBENTS CORPORATION ( Exact name of registrant as specified in its charter ) Large Accelerated Filer □ Non - accelerated Filer þ 98-0373793 ( I.R.S. Employer Identification No. ) 7 Deer Park Drive , Suite K Monmouth Junction , New Jersey 08852 ( Address of principal executive offices ) ( Zip Code ) Registrant's telephone number , including area code ( 732 ) 329-8885 Securities registered pursuant to Section 12 ( b ) of the Act : Trading Symbol CTSO Name of each exchange on which registered : The Nasdaq Stock Market LLC ( Nasdaq Capital Market ) Securities registered pursuant to Section 12 ( g ) of the Act : None Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15 ( d ) of the Act . Indicate by check mark whether the registrant ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months ( or for such shorter period that the registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes þ No Yes þ No þ Yes No Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S - T ( §232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the registrant was required to submit such files ) . þ Yes No Indicate by check mark whether the registrant is a large accelerated filer , an accelerated filer , a non - accelerated filer , or a smaller reporting company , or emerging growth company . See the definitions of " large accelerated filer , " " accelerated filer , " " smaller reporting company , " and emerging growth company in Rule 12b - 2 of the Exchange Act . Accelerated Filer Smaller reporting companyþ Emerging growth company If an emerging growth company , indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13 ( a ) of the Exchange Act Indicate by check mark whether the registrant has filed a report on and attestation to its management's assessment of the effectiveness of its internal control over financial reporting under Section 404 ( b ) of the Sarbanes - Oxley Act ( 15 U.S.C.7262 ( b ) ) by the registered public accounting firm that prepared or issued its audit report . þ Indicate by check mark whether the registrant is a shell company ( as defined in Rule 12b - 2 of the Exchange Act . ) Yes þ No The aggregate market value of the common stock of the registrant held by non - affiliates as of June 30 , 2020 was approximately $ 306,285,000 based upon the closing price reported for such date on the Nasdaq Capital Market . As of March 9 , 2021 , there were outstanding 43,263,772 shares of the registrant's common stock . Documents incorporated by reference : Portions of the registrant's definitive proxy statement to be filed pursuant to Regulation 14A within 120 days after the end of the registrant's fiscal year are incorporated by reference into Part III of this Form 10 - K and certain documents are incorporated by reference into Part IV of this Form 10 - K .