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Table of Contents ( Mark One ) ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31 , 2020 Or ☐ UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D.C. 20549 Form 10 - K TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number : 001-37539 Delaware ( State of other jurisdiction of incorporation or organization ) Global Blood Therapeutics , Inc. ( Exact name of registrant as specified in its charter ) 181 Oyster Point Boulevard , South San Francisco , California ( Address of principal executive offices ) Title of Each Class Common Stock , $ 0.001 par value 0 Registrant's telephone number , including area code : ( 650 ) 741-7700 Securities registered pursuant to Section 12 ( b ) of the Act : Trading Symbol ( s ) GBT Securities registered under Section 12 ( g ) of the Act : None 27-4825712 ( I.R.S. Employer Identification No. ) 94080 ( Zip Code ) Name of Each Exchange on Which Registered The NASDAQ Global Select Market No No > Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Yes Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15 ( d ) of the Act . Yes Indicate by check mark whether the registrant ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months ( or for such shorter period that the registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes > No Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( § 232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the registrant was required to submit such files ) . Yes No Indicate by check mark whether the registrant is a large accelerated filer , an accelerated filer , a non - accelerated filer , a smaller reporting company , or an emerging growth company . See the definitions of " large accelerated filer " , " accelerated filer " , " smaller reporting company " and " emerging growth company " in Rule 12b - 2 of the Exchange Act . Large accelerated filer Accelerated filer Non - accelerated filer Smaller reporting company Emerging growth company If an emerging growth company , indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13 ( a ) of the Exchange Act . Indicate by check mark whether the registrant has filed a report on and attestation to its management's assessment of the effectiveness of its internal control over financial reporting under Section 404 ( b ) of the Sarbanes - Oxley Act ( 15 U.S.C. 7262 ( b ) ) by the registered public accounting firm that prepared or issued its audit report . Indicate by check mark whether the registrant is a shell company ( as defined in Rule 12b - 2 of the Act . ) Yes No The aggregate market value of the common stock held by non - affiliates of the registrant was approximately $ 1,606.1 million as of June 30 , 2020 based upon the closing sale price on the NASDAQ Global Select Market reported for such date . Shares of common stock held by each executive officer and director have been excluded in that such persons may be deemed to be affiliates of the registrant . Shares of common stock held by other persons , including certain holders of more than 10 % of the outstanding shares of common stock , have not been excluded in that such persons are not deemed to be affiliates . This determination of affiliate status is not necessarily a conclusive determination for other purposes . As of February 18 , 2021 , the registrant had 62,156,860 shares of common stock , par value $ 0.001 , outstanding . DOCUMENTS INCORPORATED BY REFERENCE Portions of the registrant's definitive Proxy Statement for the registrant's 2021 Annual Meeting of Stockholders , to be filed subsequent to the date hereof with the Securities and Exchange Commission , or SEC , are incorporated by reference into Part III of this report . Such proxy statement will be filed with the SEC not later than 120 days after the end of the registrant's fiscal year ended December 31 , 2020 . ooo