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Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D.C. 20549 ( Mark One ) ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended : September 25 , 2021 FORM 10 - K TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from Delaware ( State or Other Jurisdiction of Incorporation or Organization ) or HOLOGIC , INC . ( Exact name of registrant as specified in its charter ) to Commission File Number : 1-36214 Title of Each Class Common Stock , $ 0.01 par value 04-2902449 ( I.R.S. Employer Identification No. ) 250 Campus Drive , Marlborough , Massachusetts 01752 ( Address of Principal Executive Offices ) ( Zip Code ) Registrant's Telephone Number , Including Area Code ( 508 ) 263-2900 Securities registered pursuant to Section 12 ( b ) of the Act : Trading Symbol ( s ) HOLX Securities registered pursuant to Section 12 ( g ) of the Act : None Name of Each Exchange on which Registered The NASDAQ Global Select Market Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Yes No Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15 ( d ) of the Act . Yes ☐ No | Indicate by check mark whether the registrant ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months ( or for such shorter period that the registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes No □ Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( §232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the registrant was required to submit such files ) . Yes No Indicate by check mark whether the registrant is a large accelerated filer , an accelerated filer , a non - accelerated filer , smaller reporting company , or an emerging growth company . See the definitions of " large accelerated filer , " " accelerated filer " and " smaller reporting company " in Rule 12b - 2 of the Exchange Act ( Check one ) .