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ICON ICON Reports Second Quarter 2021 Results July 21 , 2021 Highlights • Record net business wins in the quarter of $ 1,106 million , an increase of 21.6 % year on year ; a net book to bill of 1.27 . • Record closing backlog of $ 10.2 billion , an increase of 12.7 % year on year . • Quarter 2 reported revenue of $ 871.2 million representing a year on year increase of 40.5 % and 1.5 % increase on Quarter • 1 2021 . Adjusted income from operations * amounted to $ 132.9 million or 15.3 % of revenue , a year on year increase of 77.1 % . Adjusted net income attributable to the Group * was $ 113.2 million or $ 2.12 per diluted share , compared to $ 1.20 per share for the equivalent prior year period , an increase of 76.8 % . • US GAAP income from operations amounted to $ 112.9 million or 13.0 % of revenue , a year on year increase of 98.2 % . US GAAP net income attributable to the Group was $ 73.9 million or $ 1.38 per diluted share , compared to $ 0.90 per share for the equivalent prior year period , an increase of 53.3 % . • Strong cash generation resulting in a record gross cash position of $ 1,057 million . Days sales outstanding reduced to 35 days from 53 days at June 30 , 2020 . • Net business wins for PRA's Clinical Research segment for Quarter 2 including reimbursement revenue was approximately $ 1,191 million ; a net book to bill of 1.21 . Quarter 2 revenue was approximately $ 1,047 million , a year on year increase of 43.5 % . • Following completion of our acquisition of PRA Health Sciences on July 1 , 2021 , new revenue and EPS guidance is issued including PRA Health Sciences for quarters 3 and 4. Full year 2021 revenue guidance issued in the range of $ 5,300 - $ 5,500 million , representing a year over year increase of 89.5 % - 96.6 % . Full year 2021 adjusted earnings per share guidance issued in the range of $ 9.10 - $ 9.50 , representing a year over year increase of 39.4 % - 45.5 % . Adjusted earnings per share to exclude amortization , stock compensation and transaction - related / integration - related costs . * before transaction - related costs and integration - related costs . DUBLIN -- ( BUSINESS WIRE ) -- Jul . 21 , 2021-- ICON plc ( NASDAQ : ICLR ) , a world - leading healthcare intelligence and clinical research organisation , today reported its financial results for the second quarter ended June 30 , 2021 . CEO Dr. Steve Cutler commented , " ICON's quarter 2 results show continuing progress and represent a strong platform for sustained future growth . During the quarter , ICON's net business wins were a record $ 1,106 million , representing a robust book to bill of 1.27 . We grew our backlog 13 % year over year to $ 10.2 billion , revenue grew 40.5 % to $ 871 million and adjusted earnings per share increased 76.8 % year over year to $ 2.12 . As announced on 1st July , ICON's acquisition of PRA brings together two complementary organisations to create a world leading healthcare intelligence and clinical CRO . We expect to create significant long - term shareholder value by combining revenue growth from enhanced service offerings , innovative solutions and increased scale with our best in class global support services model . As a result of this acquisition we are updating our 2021 outlook with revenue guidance in the range of $ 5,300 - $ 5,500 million and adjusted earnings per share guidance in the range of $ 9.10- $ 9.50 . " Second Quarter 2021 Results Gross business wins in the second quarter were $ 1,316 million and cancellations were $ 210 million . This resulted in net business wins of $ 1,106 million and a book to bill of 1.27 . Reported revenue for Quarter 2 was $ 871.2 million . This represents a year on year increase of 40.5 % or 37.5 % on a constant currency basis . US GAAP income from operations amounted to $ 112.9 million or 13.0 % of revenue , a year on year increase of 98.2 % . Adjusted income from operations * in the quarter was $ 132.9 million or 15.3 % of revenue compared to $ 75.0 million or 12.1 % of revenue for Quarter 2 2020. This represents a year on year increase of 77.1 % . US GAAP net income attributable to the Group was $ 73.9 million or 8.5 % of revenue . Adjusted net income * attributable to the Group for the quarter was $ 113.2 million or 13.0 % of revenue compared with $ 63.6 million or 10.3 % of revenue in Quarter 2 2020. This represents year on year growth of