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IQVIA Template (V4.0.0) 100% 50% 75% 25% Bright Blue Indigo Bright Teal Bright Green Emerald 5% Charcoal Red © 2026. All rights reserved. IQVIA® is a registered trademark of IQVIA Inc. in the United States, the European Union, and various other countries. October 27, 2026 Q3 2026 Earnings Call
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IQVIA Template (V2.1.0) 100% 50% 75% 25% 2 Safe Harbor Statement for Forward-Looking Statements This presentation contains “forward-looking statements” within the meaning of the federal securities laws, including Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, including, without limitation, our full-year 2026 guidance. In this context, forward-looking statements often address expected future business and financial performance and financial condition, and often contain words such as “expect,” “assume,” “anticipate,” “intend,” “plan,” “forecast,” “believe,” “seek,” “see,” “will,” “would,” “target,” similar expressions, and variations or negatives of these words that are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Actual results may differ materially from our expectations due to a number of factors, including, but not limited to, the following: business disruptions caused by natural disasters, pandemics, and the public health policy response to any outbreak, and international conflicts or other disruptions outside of our control; most of our contracts may be terminated on short notice, and we may lose or experience delays with large client contracts or be unable to enter into new contracts; the market for our services may not grow as we expect; we may be unable to successfully develop and market new services or enter new markets; imposition of restrictions on our use of data by data suppliers or their refusal to license data to us; any failure by us to comply with contractual, regulatory or ethical requirements under our contracts, including current or future changes to data protection and privacy laws; breaches or misuse of our or our outsourcing partners’ security or communications systems; failure to meet our productivity or business transformation objectives; failure to successfully invest in growth opportunities; our ability to protect our intellectual property rights and our susceptibility to claims by others that we are infringing on their intellectual property rights; the expiration or inability to acquire third party licenses for technology or intellectual property; any failure by us to accurately and timely price and formulate cost estimates for contracts, or to document change orders; hardware and software failures, delays in the operation of our computer and communications systems or the failure to implement system enhancements; the rate at which our backlog converts to revenue; our ability to acquire, develop and implement technology necessary for our business; consolidation in the industries in which our clients operate; risks related to client or therapeutic concentration; government regulators or our customers may limit the number or scope of indications for medicines and treatments or withdraw products from the market, and government regulators may impose new regulatory requirements or may adopt new regulations affecting the biopharmaceutical industry; the risks associated with operating on a global basis, including currency or exchange rate fluctuations and legal compliance, including anti-corruption laws; risks related to the enactment of legislation or the imposition of regulations or other restrictions or actions by governments that create business uncertainty and have the potential to limit trade; changes in accounting standards; general economic conditions in the markets in which we operate, including financial market conditions, inflation, and risks related to sales to government entities; the impact of changes in tax laws and regulations; and our ability to successfully integrate, and achieve expected benefits from, our acquired businesses. In addition, we may not achieve the expected benefits of our reorganized business segment structure. For a further discussion of the risks relating to our business, see the “Risk Factors” in our annual report on Form 10-K for the fiscal year ended December 31, 2025, filed with the Securities and Exchange Commission (the "SEC"), as such factors may be amended or updated from time to time in our subsequent periodic and other filings with the SEC, which are accessible on the SEC’s website at www.sec.gov. These factors should not be construed as exhaustive and should be read in conjunction with the other cautionary statements that are included in this presentation and in our filings with the SEC. We assume no obligation to update any such forward-looking statement after the date of this release, whether as a result of new information, future developments or otherwise. Past Performance In all cases where historical results are presented or past performance is described, we note that past performance is not a reliable indicator of future results and performance. Trademarks All trademarks or service marks are the property of IQVIA or their respective owners. Solely for convenience, the trademarks, service marks and trade names are referenced without the ®, (SM) and (TM) symbols, but we will assert, to the fullest extent under applicable law, our rights or the rights of the applicable licensors to these marks. This presentation should be viewed in conjunction with IQVIA’s Q3 2026 earnings call Legal
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IQVIA Template (V2.1.0) 100% 50% 75% 25% 3 Non-GAAP Information This presentation includes information based on financial measures that are not recognized under generally accepted accounting principles in the United States (“GAAP”), such as Adjusted EBITDA, Adjusted Net Income, Adjusted Diluted Earnings per Share, Gross Leverage Ratio, Net Leverage Ratio and Free Cash Flow. Non-GAAP financial measures are presented only as a supplement to the company’s financial statements based on GAAP. Non-GAAP financial information is provided to enhance understanding of the company’s financial performance, but none of these non-GAAP financial measures are recognized terms under GAAP, and non-GAAP measures should not be considered in isolation from, or as a substitute analysis for, the company’s results of operations as determined in accordance with GAAP. The company uses non-GAAP measures in its operational and financial decision making and believes that it is useful to exclude certain items in order to focus on what it regards to be a more meaningful indicator of the underlying operating performance of the business. For example, the Company excludes all the amortization of intangible assets associated with acquired customer relationships and backlog, databases, non-compete agreements, trademarks and trade names from non-GAAP expense and income measures as such amounts can be significantly impacted by the timing and size of acquisitions. Although we exclude amortization of acquired intangible assets from our non-GAAP expenses, we believe that it is important for investors to understand that revenue generated from such intangibles is included within revenue in determining net income. As a result, internal management reports feature non-GAAP measures and are used to prepare strategic plans and annual budgets and review management compensation. The company also believes that investors may find non-GAAP financial measures useful for the same reasons, although investors are cautioned that non-GAAP financial measures are not a substitute for GAAP disclosures. The non-GAAP financial measures are not presented in accordance with GAAP. Please refer to the appendix of this presentation for reconciliations of non-GAAP financial measures contained herein to the most directly comparable GAAP measures. Our full-year 2026 guidance measures (other than revenue) are provided on a non-GAAP basis without a reconciliation to the most directly comparable GAAP measure because the company is unable to predict with a reasonable degree of certainty certain items contained in the GAAP measures without unreasonable efforts. For the same reasons, the company is unable to address the probable significance of the unavailable information. Such items include, but are not limited to, acquisition related expenses, restructuring and related expenses, stock-based compensation and other items not reflective of the company's ongoing operations. Non-GAAP measures are frequently used by securities analysts, investors and other interested parties in their evaluation of companies comparable to the company, many of which present non-GAAP measures when reporting their results. Non-GAAP measures have limitations as an analytical tool. They are not presentations made in accordance with GAAP, are not measures of financial condition or liquidity and should not be considered as an alternative to profit or loss for the period determined in accordance with GAAP or operating cash flows determined in accordance with GAAP. Non-GAAP measures are not necessarily comparable to similarly titled measures used by other companies. As a result, you should not consider such performance measures in isolation from, or as a substitute analysis for, the company’s results of operations as determined in accordance with GAAP. Legal
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IQVIA Template (V2.1.0) 100% 50% 75% 25% 4 $M, except per share data 3rd Quarter Results Q3 2026 Q3 2025 8.0% AFx 8.6% CFx Revenue Q3 2026 Q3 2025 Adjusted EBITDA(1) 8.7% AFx Dollars are at actual foreign exchange rates. AFx is actual currency. CFx is constant currency. (1) See reconciliation of non-GAAP items in the Appendix. Q3 2026 Q3 2025 11.3% AFx Adjusted Diluted EPS(1) $4,428 $4,100 $1,032 $949 $3.34 $3.00
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IQVIA Template (V2.1.0) 100% 50% 75% 25% 5 $M 3rd Quarter and Year-to-Date Revenue Dollars are at actual foreign exchange rates. AFx is actual currency, CFx is constant currency. (*) Prior period segment amounts have been recast to conform to the new segment reporting structure. Q3 YTD 2026 2025* VPY% AFx VPY% CFx 2026 2025* VPY% AFx VPY% CFx Commercial Solutions $1,789 $1,673 6.9% 7.9% $5,336 $4,896 9.0% 8.3% Research & Development Solutions $2,639 $2,427 8.7% 9.1% $7,611 $7,050 8.0% 7.4% Revenue $4,428 $4,100 8.0% 8.6% $12,947 $11,946 8.4% 7.7%
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IQVIA Template (V2.1.0) 100% 50% 75% 25% 6 $M, except per share data 3rd Quarter and Year-to-Date Profit Dollars are at actual foreign exchange rates. (1) See reconciliations of non-GAAP items in Appendix. Q3 YTD 2026 2025 2026 2025 Adjusted EBITDA (1) $1,032 $949 $2,958 $2,742 Net Income $350 $331 $880 $846 Diluted Earnings per Share $2.10 $1.93 $5.24 $4.86 Adjusted Net Income (1) $557 $515 $1,576 $1,480 Adjusted Diluted Earnings per Share (1) $3.34 $3.00 $9.38 $8.50
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IQVIA Template (V2.1.0) 100% 50% 75% 25% 7 $B, Prior period amounts have been recast to conform to the new segment reporting structure R&DS Last-Twelve-Month Net New Bookings, Net New Bookings & Next-Twelve-Month Revenue Q3 2025 Q3 2026 Net New BookingsLast-Twelve-Month Net Bookings Q3 2025 Q3 2026 Dollars are at actual foreign exchange rates. (1) Next-Twelve-Month Revenue reflects management’s forecast of the Revenue that will be generated from the backlog as of a given date in the next 12 months. Q3 2025 Q3 2026 $10.3 $11.7 $8.5 $9.4 $2.8 $3.2 +15%+14% +10% Next-Twelve-Month Revenue(1)
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IQVIA Template (V2.1.0) 100% 50% 75% 25% 8 $M 3rd Quarter Balance Sheet and Cash Flow Items and Metrics Dollars are at actual foreign exchange rates. (1) Calculated using last-twelve-month Adjusted EBITDA. (2) See reconciliation of non-GAAP items in the Appendix. Cash & Cash Equivalents $2,249 Gross Debt $16,067 Net Debt $13,818 Gross Leverage Ratio (1) 4.01x Net Leverage Ratio (1) 3.45x Net Cash Provided by Operating Activities $825 Capital Expenditures $158 Free Cash Flow (2) $667
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IQVIA Template (V2.1.0) 100% 50% 75% 25% 9 Updated financial guidance assumes October 26, 2026 foreign exchange rates remain in effect for the guidance period. Revenue $17,350 – $17,500 Adj. EBITDA $4,025 – $4,055 Adj. Diluted EPS $12.90 – $13.00 Full-Year 2026 Guidance $M, except per share data
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IQVIA Template (V2.1.0) 100% 50% 75% 25% 10 Q&A
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IQVIA Template (V2.1.0) 100% 50% 75% 25% 11 Net Income to Adjusted EBITDA Reconciliation Three Months Ended September 30, Nine Months Ended September 30, (in millions) 2026 2025 2026 2025 Net Income Attributable to IQVIA Holdings Inc. $ 350 $ 331 $ 880 $ 846 Provision for income taxes 76 76 195 193 Depreciation and amortization 321 286 901 827 Interest expense, net 191 176 563 502 (Income) loss in unconsolidated affiliates (42) — (65) 14 Income from noncontrolling interests 2 1 5 1 Stock-based compensation 83 55 243 187 Other expense (income), net (1) 2 (21) 43 23 Loss on extinguishment of debt — — 3 4 Restructuring and related expenses (2) 41 30 161 114 Acquisition related expenses 8 15 29 31 Adjusted EBITDA $ 1,032 $ 949 $ 2,958 $ 2,742 (1) Reflects certain non-operating income items, revaluations of contingent consideration and certain non-recurring expenses. (2) Reflects restructuring costs as well as accelerated expenses related to lease exits.
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IQVIA Template (V2.1.0) 100% 50% 75% 25% 12 Net Income to Adj. Net Income and Per Share Data Reconciliation (1) Reflects all the amortization of acquired intangible assets. (2) Reflects certain non-operating income items, revaluations of contingent consideration and certain non-recurring expenses. (3) Reflects restructuring costs as well as accelerated expenses related to lease exits. Three Months Ended September 30, Nine Months Ended September 30, (in millions, except per share data) 2026 2025 2026 2025 Net Income Attributable to IQVIA Holdings Inc. $ 350 $ 331 $ 880 $ 846 Provision for income taxes 76 76 195 193 Purchase accounting amortization (1) 163 138 436 394 (Income) loss in unconsolidated affiliates (42) — (65) 14 Income from noncontrolling interests 2 1 5 1 Stock-based compensation 83 55 243 187 Other expense (income), net (2) 2 (21) 43 23 Loss on extinguishment of debt — — 3 4 Restructuring and related expenses (3) 41 30 161 114 Acquisition related expenses 8 15 29 31 Adjusted Pre Tax Income $ 683 $ 625 $ 1,930 $ 1,807 Adjusted tax expense (124) (109) (349) (326) Income from noncontrolling interests (2) (1) (5) (1) Adjusted Net Income $ 557 $ 515 $ 1,576 $ 1,480 Adjusted earnings per share attributable to common stockholders: Basic $ 3.38 $ 3.03 $ 9.47 $ 8.57 Diluted $ 3.34 $ 3.00 $ 9.38 $ 8.50 Weighted average common shares outstanding: Basic 164.7 170.2 166.4 172.6 Diluted 167.0 171.7 168.0 174.1
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IQVIA Template (V2.1.0) 100% 50% 75% 25% 13 Operating Cash Flow to Free Cash Flow Reconciliation Three Months Ended September 30, Nine Months Ended September 30, (in millions) 2026 2025 2026 2025 Net Cash provided by Operating Activities $ 825 $ 908 $ 2,001 $ 1,919 Acquisition of property, equipment and software (158) (136) (483) (429) Free Cash Flow $ 667 $ 772 $ 1,518 $ 1,490
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IQVIA Template (V2.1.0) 100% 50% 75% 25% 14 Leverage Ratios (in millions) Gross Debt, net of Unamortized Discount and Debt Issuance Costs, as of September 30, 2026 $ 16,067 Net Debt as of September 30, 2026 $ 13,818 Adjusted EBITDA for the twelve months ended September 30, 2026 $ 4,004 Gross Leverage Ratio (Gross Debt/LTM Adjusted EBITDA) 4.01x Net Leverage Ratio (Net Debt/LTM Adjusted EBITDA) 3.45x