Page 1

United States Securities and Exchange Commission Washington , D.C. 20549 Form 10 - K Annual report pursuant to Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 for the fiscal year ended December 31 , 2020 Commission file number 001-06351 Indiana ( State or other jurisdiction of incorporation or organization ) Title of Each Class Common Stock ( no par value ) 1.000 % Notes due 2022 7 1 / 8 % Notes due 2025 1.625 % Notes due 2026 2.125 % Notes due 2030 0.625 % Notes due 2031 6.77 % Notes due 2036 1.700 % Notes due 2049 ELI LILLY AND COMPANY ( Exact name of Registrant as specified in its charter ) Registrant's telephone number , including area code ( 317 ) 276-2000 Securities registered pursuant to Section 12 ( b ) of the Exchange Act : Lilly Corporate Center , Indianapolis , Indiana 46285 ( Address and zip code of principal executive offices ) 35-0470950 ( I.R.S. Employer Identification No. ) Trading Symbol ( s ) . LLY LLY22 LLY25 LLY26 LLY30 LLY31 LLY36 LLY49A Large accelerated filer Non - accelerated filer Name of Each Exchange On Which Registered New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange Securities registered pursuant to Section 12 ( g ) of the Exchange Act : None Indicate by check mark if the Registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Yes No Indicate by check mark if the Registrant is not required to file reports pursuant to Section 13 or 15 ( d ) of the Exchange Act . Yes No Indicate by check mark whether the Registrant ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Exchange Act during the preceding 12 months ( or for such shorter period that the Registrant was required to file such reports ) and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes No Indicate by check mark whether the Registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( § 232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the Registrant was required to submit such files ) . Yes > No Indicate by check mark whether the Registrant is a large accelerated filer , an accelerated filer , a non - accelerated filer , a smaller reporting company , or an emerging growth company . See the definitions of " large accelerated filer , " " accelerated filer , " " smaller reporting company , " and " emerging growth company " in Rule 12b - 2 of the Exchange Act . Accelerated filer Smaller reporting company Emerging growth company 0 0 If an emerging growth company , indicate by check mark if the Registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13 ( a ) of the Exchange Act . Indicate by check mark whether the Registrant has filed a report on and attestation to its management's assessment of the effectiveness of its internal control over financial reporting under Section 404 ( b ) of the Sarbanes - Oxley Act ( 15 U.S.C. 7262 ( b ) ) by the registered public accounting firm that prepared or issued its audit report . Indicate by check mark whether the Registrant is a shell company ( as defined in Rule 12b - 2 of the Exchange Act ) : Yes No Aggregate market value of the common equity held by non - affiliates computed by reference to the price at which the common equity was last sold as of the last business day of the Registrant's most recently completed second fiscal quarter : approximately $ 138,907,000,000 . Number of shares of common stock outstanding as of February 12 , 2021 : 958,425,693 Portions of the Registrant's Proxy Statement for the 2021 Annual Meeting of Shareholders have been incorporated by reference into Part III of this report .