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Second - Quarter Highlights , Year - over - Year : Total revenues of $ 66.6 billion increased 9 % ● ● ● ● Earnings per diluted share from continuing operations of $ 1.71 decreased $ 1.83 Adjusted Earnings per Diluted Share of $ 6.15 increased 28 % Fiscal 2022 Outlook : Increased fiscal 2022 Adjusted Earnings per Diluted Share guidance range to $ 21.95 to $ 22.55 , from the previous range of $ 19.80 to $ 20.40 , representing 27.5 % to 31 % growth compared to prior year . MCKESSON REPORTS FISCAL 2022 SECOND - QUARTER RESULTS O Fiscal 2022 Adjusted Earnings per Diluted Share guidance includes approximately $ 2.30 to $ 3.05 of impacts attributable to the following : O O $ 0.50 to $ 0.75 related to COVID - 19 tests and impairments for personal protective equipment and related products $ 0.49 related to year - to - date gains or losses associated with McKesson Ventures ' equity investments Excluding the impacts of the above items from both fiscal 2022 guidance and fiscal 2021 results , indicates 20 % to 29 % forecasted growth . MCKESSON $ 1.30 to $ 1.80 related to the U.S. government's COVID - 19 vaccine distribution , kitting , and storage programs IRVING , Texas , November 1 , 2021 - McKesson Corporation ( NYSE : MCK ) today reported strong second - quarter results for the period ended September 30 , 2021 . Fiscal 2022 Second - Quarter Result Summary ( $ in millions , except per share amounts ) Revenues Income from Continuing Operations ¹ 1,2 Adjusted Earnings Earnings per Diluted Share ¹ Adjusted Earnings per Diluted Share ¹ , 2 Second - Quarter FY22 FY21 $ 66,576 $ 60,808 577 784 3.54 4.80 Change FY22 9 % $ 129,250 ( 54 ) 22 756 1,838 4.82 11.71 ( 52 ) 28 Year - to - Date FY21 $ 116,487 1,022 1,237 6.26 7.58 Change 11 % 267 958 1.71 6.15 ¹ Reflects continuing operations attributable to McKesson , net of tax 2 Represents a non - GAAP financial measure ; refer to the reconciliations of non - GAAP financial measures included in accompanying schedules ( 26 ) 49 ( 23 ) 54 " Our enterprise strategy is enabling us to successfully navigate a dynamic environment . McKesson delivered strong second - quarter results , including double - digit Adjusted Operating Profit growth across all segments , " said Brian Tyler , chief executive officer . " We remain committed to investing in our growth strategies of biopharma services and oncology ecosystems , while simultaneously increasing shareholder returns . "