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Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D.C. 20549 Form 10 - K ( Mark One ) ☑ ☐ ANNUAL REPORT PURSUANT TO SECTION 13 , OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31 , 2020 OR TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from Delaware Commission file number : 001-38940 MORPHIC HOLDING , INC . to ( Exact name of registrant as specified in its charter ) ( State or other jurisdiction of Incorporation or Organization ) 35 Gatehouse Drive , A2 Waltham , MA ( Address of Principal Executive Offices ) Title of each class 47-3878772 ( I.R.S. Employer Identification No. ) 02451 ( Zip Code ) Registrant's telephone number , including area code : ( 781 ) 996-0955 Securities registered pursuant to Section 12 ( b ) of the Exchange Act : Common Stock , par value $ 0.0001 per share Trading symbol ( s ) MORF Name of each exchange on which registered The Nasdaq Global Market Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Yes □ No Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15 ( d ) of the Act . Yes □ No ☑ Indicate by check mark whether the registrant ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months ( or for such shorter period that the registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes > No □ Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( Section 232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the registrant was required to submit such files ) . Yes > No □ Indicate by check mark whether the registrant is a large accelerated filer , an accelerated filer , a non - accelerated filer , a smaller reporting company , or an emerging growth company . See the definitions of " large accelerated filer , " " accelerated filer , ” “ smaller reporting company , " and " emerging growth company " in Rule 12b - 2 of the Exchange Act . Large accelerated filer Non - accelerated filer ☑ Accelerated filer □ Smaller reporting company Emerging growth company If an emerging growth company , indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13 ( a ) of the Exchange Act . □ Indicate by check mark whether the registrant has filed a report on and attestation to its management's assessment of the effectiveness of its internal control over financial reporting under Section 404 ( b ) of the Sarbanes - Oxley Act ( 15 U.S.C. 7262 ( b ) ) by the registered public accounting firm that prepared or issued its audit report . ☐ Indicate by check mark whether the registrant is a shell company ( as defined in Exchange Act Rule 12b - 2 ) . Yes □ No ☑ The aggregate market value ( approximate ) of the registrant's common equity held by non - affiliates based on the closing price of a share of the registrant's common stock for as reported on The Nasdaq Global Market on June 30 , 2020 ( the last business day of the registrant's most recently completed second fiscal quarter ) was $ 318,431,000 . The number of shares outstanding of the registrant's Common Stock as of February 24 , 2021 was 32,449,889 .