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( Mark One ) ■ UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D.C. 20549 ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31 , 2020 FORM 10 - K TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 1-3619 2Pfizer Title of each class Common Stock , $ .05 par value 0.250 % Notes due 2022 1.000 % Notes due 2027 Delaware ( State or other jurisdiction of incorporation or organization ) Large Accelerated filer > PFIZER INC . ( Exact name of registrant as specified in its charter ) 235 East 42nd Street , New York , New York 10017 ( Address of principal executive offices ) ( zip code ) ( 212 ) 733-2323 ( Registrant's telephone number , including area code ) Accelerated filer Securities registered pursuant to Section 12 ( b ) of the Act : Trading Symbol ( s ) . PFE PFE22 PFE27 ( I.R.S. Employer Identification Number ) Securities registered pursuant to Section 12 ( g ) of the Act : None Yes > No Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15 ( d ) of the Act . Yes No Indicate by check mark whether the registrant ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months ( or for such shorter period that the registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes No 13-5315170 Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( §232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the registrant was required to submit such files . ) Yes No Indicate by check mark whether the registrant is a large accelerated filer , an accelerated filer , a non - accelerated filer , a smaller reporting company or an emerging growth company . See the definitions of " large accelerated filer , " " accelerated filer " , " smaller reporting company " and " emerging growth company " in Rule 12b - 2 of the Exchange Act . Non - accelerated filer Name of each exchange on which registered New York Stock Exchange New York Stock Exchange New York Stock Exchange Smaller reporting company Emerging growth company If an emerging growth company , indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13 ( a ) of the Exchange Act . Portions of the Proxy Statement for the 2021 Annual Meeting of Shareholders Indicate by check mark whether the registrant has filed a report on and attestation to its management's assessment of the effectiveness of its internal control over financial reporting under Section 404 ( b ) of the Sarbanes - Oxley Act ( 15 U.S.C. 7262 ( b ) ) by the registered public accounting firm that prepared or issued its audit report . < DOCUMENTS INCORPORATED BY REFERENCE No | Indicate by check mark whether the registrant is a shell company ( as defined in Rule 12b - 2 of the Exchange Act ) . Yes The aggregate market value of the voting stock held by non - affiliates of the registrant , computed by reference to the closing price as of the last business day of the registrant's most recently completed second fiscal quarter , June 28 , 2020 , was approximately $ 169 billion . This excludes shares of common stock held by directors and executive officers at June 28 , 2020. Exclusion of shares held by any person should not be construed to indicate that such person possesses the power , directly or indirectly , to direct or cause the direction of the management or policies of the registrant , or that such person is controlled by or under common control with the registrant . The registrant has no non - voting common stock . The number of shares outstanding of the registrant's common stock as of February 23 , 2021 was 5,577,629,491 shares of common stock , all of one class . Part III