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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D.C. 20549 FORM 10 - K ( Mark One ) ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31 , 2020 OR TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001-38293 SCPHARMACEUTICALS INC . ( Exact name of registrant as specified in its Charter ) Delaware ( State or other jurisdiction of incorporation or organization ) 2400 District Avenue , Suite 310 Burlington , Massachusetts ( Address of principal executive offices ) Title of each class Common stock , par value $ 0.0001 46-5184075 ( I.R.S. Employer Identification No. ) 01803 ( Zip Code ) Registrant's telephone number , including area code : ( 617 ) 517-0730 Securities registered pursuant to Section 12 ( b ) of the Act : Trading Symbol ( s ) SCPH Securities registered pursuant to Section 12 ( g ) of the Act : None ( Title of class ) X Name of each exchange on which registered The Nasdaq Global Select Market Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . YES NO Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or 15 ( d ) of the Act . YES NO Indicate by check mark whether the registrant : ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months ( or for such shorter period that the registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . YES NO Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( §232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the registrant was required to submit such files ) . YES > NO Indicate by check mark whether the registrant is a large accelerated filer , an accelerated filer , a non - accelerated filer , a smaller reporting company , or an emerging growth company . See the definitions of " large accelerated filer , " " accelerated filer , ” “ smaller reporting company , " and " emerging growth company " in Rule 12b - 2 of the Exchange Act . Large accelerated filer Non - accelerated filer Accelerated filer Smaller reporting company Emerging growth company X If an emerging growth company , indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13 ( a ) of the Exchange Act . > Indicate by check mark whether the registrant has filed a report on and attestation to its management's assessment of the effectiveness of its internal control over financial reporting under Section 404 ( b ) of the Sarbanes - Oxley Act ( 15 U.S.C. 7262 ( b ) ) by the registered public accounting firm that prepared or issued its audit report . Indicate by check mark whether the registrant is a shell company ( as defined in Rule 12b - 2 of the Exchange Act ) . YES NO > The aggregate market value of the registrant's voting and non - voting common equity held by non - affiliates of the registrant computed by reference to the price at which the common equity was last sold as of the last business day of the registrant's most recently completed second fiscal quarter ( June 30 , 2020 ) was $ 112,980,004 . The number of shares of registrant's Common Stock outstanding as of March 22 , 2021 was 27,355,453 . DOCUMENTS INCORPORATED BY REFERENCE The following documents ( or parts thereof ) are incorporated by reference into the following parts of this Form 10 - K : Certain information required in Part III of this Annual Report on Form 10 - K is incorporated from the registrant's Definitive Proxy Statement for the 2021 Annual Meeting of Shareholders .