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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D.C. 20549 ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31 , 2020 or TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from Delaware ( State or other jurisdiction of incorporation or organization ) Form 10 - K 7000 Marina Blvd. Brisbane , California ( Address of principal executive offices ) SANGAMO THERAPEUTICS , INC . ( Exact name of registrant as specified in its charter ) ( Registrant's Securities registered pursuant to Section 12 ( b ) of the Act : Title of each class Common Stock , par value $ 0.01 per share Commission file number : 000-30171 to ( 510 ) 970-6000 telephone number , including area code ) Trading Symbol ( s ) . SGMO X ☐ 68-0359556 ( I.R.S. Employer Identification No. ) 94005 ( Zip Code ) Name of each exchange on which registered Nasdaq Global Select Market Securities registered pursuant to Section 12 ( g ) of the Act : None No No 因 Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Yes Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15 ( d ) of the Exchange Act . Yes Indicate by check mark whether the registrant ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months ( or for such shorter period that the registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes No No Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( §232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the registrant was required to submit such files ) . Yes > Indicate by check mark whether the registrant is a large accelerated filer , an accelerated filer , a non - accelerated filer , a smaller reporting company , or an emerging growth company . See the definition of " large accelerated filer , " " accelerated filer , " " smaller reporting company " and " emerging growth company " in Rule 12b - 2 of the Exchange Act . Large accelerated filer Non - accelerated filer Accelerated filer Smaller reporting company Emerging growth company 0 0 0 If an emerging growth company , indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13 ( a ) of the Exchange Act . Indicate by check mark whether the registrant has filed a report on and attestation to its management's assessment of the effectiveness of its internal control over financial reporting under Section 404 ( b ) of the Sarbanes - Oxley Act ( 15 U.S.C. 7262 ( b ) ) by the registered public accounting firm that prepared or issued its audit report . Indicate by check mark whether the registrant is a shell company ( as defined in Rule 12b - 2 of the Act ) . Yes No 因 The aggregate market value of the common stock held by non - affiliates of the registrant based upon the closing sale price of the common stock on June 30 , 2020 ( the last business day of the registrant's most recently completed second fiscal quarter ) , as reported on the Nasdaq Global Select Market was $ 1,262,431,735 . For purposes of this calculation , directors and executive officers of the registrant have been deemed affiliates . This determination of affiliate status is not necessarily a conclusive determination for other purposes . As of February 19 , 2021 , a total of 143,251,243 shares of common stock , $ 0.01 par value per share were outstanding . DOCUMENTS INCORPORATED BY REFERENCE Certain information required by Part III , Items 10-14 of this Form 10 - K is incorporated by reference to the registrant's definitive Proxy Statement for the 2021 Annual Meeting of Stockholders to be filed with the Securities and Exchange Commission pursuant to Regulation 14A not later than 120 days after the end of the fiscal year covered by this Form 10 - K , provided that if such Proxy Statement is not filed within such period , such information will be included in an amendment to this Form 10 - K to be filed within such 120 - day period .