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☐ ☐ UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D.C. 20549 FORM 20 - F REGISTRATION STATEMENT PURSUANT TO SECTION 12 ( b ) OR ( g ) OF THE SECURITIES EXCHANGE ACT OF 1934 OR ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31 , 2020 OR TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 OR SHELL COMPANY REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of event requiring this shell company report Title of each class Commission file number 001-38367 Sol - Gel Advanced Topical Therapy Sol - Gel Technologies Ltd. ( Exact name of Registrant as specified in its charter ) N / A ( Translation of Registrant's name into English ) Israel ( Jurisdiction of incorporation or organization ) 7 Golda Meir St. , Weizmann Science Park , Ness Ziona , 7403650 , Israel ( Address of principal executive offices ) Gilad Mamlok , Chief Financial Officer 7 Golda Meir St. , Weizmann Science Park , Ness Ziona , 7403650 , Israel Tel : 972-8-9313429 ; Fax : 972-153-523044444 ( Name , Telephone , E - mail and / or Facsimile number and Address of Company Contact Person ) Ordinary Shares , par value NIS 0.1 per share Securities registered or to be registered pursuant to Section 12 ( b ) of the Act . Trading Symbol ( s ) SLGL Name of each exchange on which registered The Nasdaq Stock Market LLC