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X 0 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON , DC 20549 ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 FORM 10 - K For the fiscal year ended December 31 , 2020 or TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from COMMISSION FILE NO . 001-36905 Delaware ( STATE OR OTHER JURISDICTION OF INCORPORATION OR ORGANIZATION ) SeaSpine Holdings Corporation ( EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER ) Title of Each Class Common Stock to 5770 Armada Drive , Carlsbad , CA 92008 , USA ( Address of principal executive offices ) ( zip code ) ( country ) REGISTRANT’S TELEPHONE NUMBER , INCLUDING AREA CODE : ( 760 ) 727-8399 47-3251758 ( I.R.S. EMPLOYER IDENTIFICATION NO . ) SECURITIES REGISTERED PURSUANT TO SECTION 12 ( b ) OF THE ACT : Trading Symbol ( s ) . SPNE Name of Exchange on Which Registered The Nasdaq Global Select Market SECURITIES REGISTERED PURSUANT TO SECTION 12 ( g ) OF THE ACT : NONE Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Yes o No x Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or 15 ( d ) of the Act . Yes o No x 1 Indicate by check mark whether the registrant : ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months ( or for such shorter period that the registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes x No o Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( §232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the registrant was required to submit such files ) . Yes x No o