Welcome to the Fourth Quarter 2024 Stryker Earnings Call. My name is Luke, and I'll be your operator for today's call. At this time, all participants are in a listen-only mode. The following conference will conduct a question-and-answer session. The conference call will be recorded for replay purposes. For your planning purposes and given the amount of content we have to cover, in the event the call runs long, we plan to end the call no later than 6:00 P.M. EST. Before we begin, I'd like to remind you that discussions during this conference call will include forward-looking statements. Factors that could cause actual results to differ materially are discussed in the most recent filings with the SEC. Also, the discussions will include certain non-GAAP financial measures. Reconciliation to most directly comparable GAAP financial measures can be found in today's press release. That's an exhibit to Stryker's current report on Form 8-K filed today with the SEC. I'd now like to turn over the call to Mr. Kevin Lobo, Chair and Chief Executive Officer. You may proceed, sir. Welcome to Stryker's Fourth Quarter Earnings Call. Joining me today are Glenn Boehnlein, Stryker CFO; Andy Pierce, Group President, MedSurg and Neurotechnology; and Jason Beach, Vice President of Finance and Investor Relations. For today's call, I'll provide opening comments, followed by Andy, who will expand on our strategic rationale for the pending Inari acquisition. Jason will then follow with the trends we saw during the quarter and some product updates. Finally, Glenn will offer further details on our 2024 results and 2025 guidance, as well as financial elements of Inari Medical and Spine, before we open the call to Q&A. First, as you saw in our press release, Glenn has decided to retire from Stryker effective April 1st after a very successful nine-year tenure as our CFO. He'll be replaced by Preston Wells, who most of you know from his time in the investor relations role. I would like to thank Glenn for his outstanding leadership and great partnership with me and Stryker leaders as we grew the company significantly, delivered consistent, strong financial results, and have positioned it very well for the future. Now, let's move to our 2024 results, which were excellent both for Q4 and the full year. Against double-digit comparatives from a year ago, organic sales growth exceeded 10% for both Q4 and the full year. Globally, for the full year, our Instruments, Endoscopy, Medical, Neurocranial, and Trauma and Extremities businesses all delivered double-digit organic sales growth. Full-year U.S. organic sales growth was an impressive 10.6%, and international organic sales growth was 8.8%. International results were led by strong performances in Canada, Emerging Markets, and Europe. International continues to represent a significant opportunity for both our legacy businesses and recent acquisitions. We also had excellent earnings performance. Including the dilutive impacts from the seven acquisitions that we completed in 2024, we exceeded our adjusted operating margin goals, delivering an improvement of 200 basis points in Q4 and 110 basis points for the full year versus 2023. Our quarterly and full-year adjusted EPS of $4.01 and $12.19 represents 16% growth for Q4 and 15% growth compared to the full year of 2023. This comprehensive performance demonstrates the durability of our high-growth offense, driven by organic innovation, focused M&A, and terrific commercial execution, as well as strong earnings power. We have momentum entering 2025 and expect to continue delivering sales growth at the high end of medtech, which is reflected in our full-year 2025 guidance of organic sales growth of 8% to 9%. This growth, combined with continuing operating margin expansion, translates to an adjusted EPS of $13.45-$13.70 per share before considering the impact of Inari Medical, which Glenn will cover. We also announced an agreement to sell our spinal implants business, which has faced challenges in achieving our performance expectations. This sale will place the spinal implants business in the hands of new owners that have extensive experience in the spine market, and it allows us to better align our resources. We continue to be excited about interventional spine, which is one of our fastest-growing businesses and was bolstered by the recent acquisition of Vertos Medical. Additionally, we remain committed to enabling technologies for the spine market, including our Q Guidance system, Copilot, and Mako Spine. These portfolio decisions reflect a continuation of our strategy to drive category leadership in attractive, high-growth end markets. I will now turn the call over to Andy. Thanks, Kevin. Our entry into the peripheral vascular market is a logical adjacency to our neurovascular division, given their complementary product portfolios and parallel sites of service. With the acquisition of Inari, Stryker will be a leading player in the fast-growing area of mechanical thrombectomy treatment for venous thromboembolism, or VTE. Mechanical thrombectomy for VTE represents a $15 billion addressable opportunity globally, with the U.S. comprising nearly $6 billion of that opportunity. Today, less than one-fifth of treatments for VTE are addressed with mechanical thrombectomy, and we therefore believe this opportunity will expand over time as hospitals and clinicians look to elevate the standard of care for VTE. We believe Inari solutions, which are supported by clinical research demonstrating their effectiveness, represent a significant opportunity for our portfolio. Since bringing its ClotTriever and FlowTriever products to market in 2017, Inari has seen tremendous revenue growth in excess of 20% annually, with a gross margin profile of approximately 85%. In addition to its treatments for VTE, Inari has invested in four exciting therapies to address unmet needs in other patient populations. These emerging therapies include chronic venous disease, dialysis access management, acute limb ischemia, and chronic limb-threatening ischemia. Together, they represent over $5 billion of incremental market segment opportunity globally. We believe Stryker's international presence can help Inari more rapidly into global markets. In recent years, Inari has made strides globally and is currently helping improve patient outcomes in over 30 markets, primarily in Europe and certain parts of Asia. Its international business is approximately 7% of sales. Stryker has long been a global leader in interventional neurovascular procedures, and with the addition of Inari, we will be equipped with a more comprehensive interventional endovascular portfolio. By leveraging the R&D and clinical capabilities of both organizations, we will have a greater opportunity to accelerate innovation and meet customer needs. From a commercial perspective, we are excited about the great synergies that exist between our teams. Inari brings significant operational infrastructure, which includes a commercial organization with attractive call points, including interventional radiologists, vascular surgeons, and interventional cardiologists. Inari's strong commercial model and patient-focused mission align well with Stryker's culture and our go-to-market strategy in neurovascular. Finally, I would like to thank and recognize Drew Hykes and the entire Inari leadership team for building a strong, mission-driven company that is improving patient lives. Inari has done an incredible job establishing the segment and driving adoption through extensive clinical studies and commercial excellence over the last 10-plus years. I'd also like to thank the Stryker team for their tremendous efforts in bringing together our two companies. With our track record in M&A, we have conviction in our ability to drive a successful integration, deliver innovative solutions to our customers, and create significant shareholder value. With our long history of investing in customer-focused technologies, we look forward to achieving best-in-class performance through a world-class sales force, a highly complementary and clinically compelling product portfolio, and an exciting pipeline to ensure we continue to grow this segment. And with that, I will now turn the call over to Jason. Thanks, Andy. My comments today will focus on providing an update on the current environment, as well as Mako, an update on product launches, and an adjustment to our external reporting. Procedural volumes remained healthy in the fourth quarter, and we continue to expect the markets will remain strong in 2025, underscored by the continued adoption in robotic-assisted surgery, favorable demographics, and healthy levels of patient activity. Additionally, demand for our capital products remained robust, with strong organic growth in Medical, Instruments and Endoscopy in the quarter and double-digit growth for the full year across all three businesses. Hospital CapEx budgets are healthy, and our capital order book remains elevated as we enter 2025. Next, specific to Mako, we had another record quarter and year of installations in the U.S. and worldwide. The progress of our Mako offense, including our direct-to-consumer campaign, has resulted in strong growth of our installed base alongside continued increases in utilization. In the U.S., we are approaching two-thirds of knees and one-third of hips performed using Mako as we exited the year. Globally, we exited the year with just over 45% of knees and approximately 20% of hips performed using Mako. We have momentum, and significant opportunities remain as Mako adoption increases. Mako Spine completed its first cases in October, and we received excellent surgeon feedback. We will continue to progress through our limited market release and remain on track for full U.S. commercial launch in the second half of the year. Next, we received approval from the FDA for our Mako Shoulder application and were able to perform our first cases in December. We are excited to now offer a complete ecosystem for shoulders, which includes Blueprint, our pre-planning software, Mako Shoulder, and a leading portfolio of shoulder implants. As a reminder, 2025 will also be a limited launch year for Mako Shoulder as we carefully gain clinical experience. We expect a full launch in the U.S. by Q1 of 2026. We have continued to see positive momentum driven by our recent product launches. Our Pangea plating system has seen robust customer interest since its launch, driving strong sales growth. Additionally, our LIFEPAK 35 defibrillator and monitor continues to draw interest, driving meaningful sales performance in the quarter along with a robust order book. Lastly, we have adjusted our external reporting to better align with how we are organized internally and to reflect the pending divestiture of the spinal implants business. Effective in the fourth quarter, our spine-enabling technologies results are reported as part of other Orthopaedics, and Interventional Spine results are reported as part of Neurocranial. As a result, Spinal Implants is now reported separately within Orthopaedics. With that, I will now turn the call over to Glenn. Thanks, Jason. Today, I will focus my comments on our fourth quarter financial results and the related drivers. Our detailed financial results have been provided in today's press release. Our organic sales growth was 10.2% in the quarter compared to 11.4% in the fourth quarter of 2023. This quarter had one more selling day than 2023. We had a 1.1% favorable impact from pricing, with both MedSurg and Neurotechnology and Orthopaedics segments contributing positive pricing for the quarter. Foreign currency had a 0.5% unfavorable impact on sales. In the quarter, U.S. organic sales growth was 10.9%. International organic sales growth was 7.9% and was led by positive sales momentum in Canada, Europe, and our emerging markets. For the year, our organic sales growth was also 10.2% against a very strong comparable of 11.5% last year. U.S. full-year organic growth was 10.6%, and international growth was 8.8%. For the full year, the impact from price was favorable 1.1%. Foreign currency had a 0.5% unfavorable impact, and 2024 had one more selling day than 2023. Our fourth quarter adjusted EPS was $4.01, was up 15.9% from 2023, driven by higher gross margins and the continued expansion of operating margins. Foreign currency translation had an unfavorable impact of 5 cents. Our full-year adjusted EPS of $12.19 was up 15% from 2023, reflecting the favorable impact of sales growth and operating margin expansion, partially offset by the unfavorable impact of foreign currency exchange translation of 13 cents. Now, I will provide some more highlights around our quarterly segment performance. In the quarter, MedSurg and Neurotechnology had constant currency sales growth of 11.1% and organic sales growth of 10.1%, which included 11.5% of U.S. organic growth and 5.8% of international organic growth. Instruments had U.S. organic sales growth of 8.8%, with healthy growth in both the surgical technologies and Orthopedic implants businesses. From a product perspective, sales growth was led by smoke evacuation, waste management, power tools, and Steri-Shield. Endoscopy had U.S. organic sales growth of 12.9%, led by strong growth across all businesses. Growth in the quarter was fueled by robust demand for our OR infrastructure and renovations and the continued success of our 1788 video platform and sports medicine shoulder products. Medical had U.S. organic sales growth of 11.1%, driven by double-digit performances in the emergency care and Sage businesses. From a product perspective, the medical business was led by strong sales growth in beds, Sage products, transport capital, and defibrillators. LIFEPAK 35 continues to drive excitement in the market with a strong and accelerating order pipeline. Neurovascular had U.S. Organic sales growth of 12%, reflecting a strong performance in our hemorrhagic business and improvement against competitive pressures in our ischemic business. Neurocranial had U.S. organic sales growth of 13.3%, led by strong growth in our bone mill, high-speed drills, bipolar forceps, craniomaxillofacial, and Interventional Spine products. As a reminder, our growth numbers now reflect the changes that Jason discussed earlier, with Interventional Spine now reported as part of our Neurocranial division. Internationally, MedSurg and Neurotechnology had organic sales growth of 5.8%, led by growth in our instruments and Endoscopy businesses. Geographically, this included strong performances in Canada and the United Kingdom. Orthopaedics had constant currency sales growth of 11.3% and organic sales growth of 10.2%, which included organic growth of 10% in the U.S. and 10.5% internationally. Our knee business grew 8.5% organically, reflecting our market-leading position in robotic-assisted knee procedures and momentum from the continued strength of our new Mako installations. Our U.S. hips business grew 7.1% organically, fueled by the continued success of our Insignia hip stem and momentum of our Mako robotic hip platform. Our U.S. trauma and extremities business grew 16.2% organically, with very strong double-digit sales growth in our core trauma and upper extremities businesses. The performance of Pangea continues to ramp amid robust interests and adoption of this differentiated plating portfolio. Our U.S. spinal implants business grew 2.3% organically in the quarter. Our U.S. other ortho business, which now includes enabling technologies, grew 1.3% organically, primarily driven by Mako deal mix and a decline in bone cement. Internationally, Orthopedics grew 10.5% organically, including strong performances in our emerging markets, Australia, New Zealand, Europe, and Canada. Now, I will focus on operating highlights in the fourth quarter. Our adjusted gross margin of 65.3% was favorable by 140 basis points compared to the fourth quarter of 2023. This improvement was primarily driven by positive pricing, manufacturing cost improvements, and mix. Adjusted R&D spending was 5.3% of sales, which was 30 basis points lower than the fourth quarter of 2023. Our adjusted SG&A was 30.8% of sales, which was 20 basis points lower than the fourth quarter of 2023. In summary, for the quarter, our adjusted operating margin was 29.2% of sales, which was 200 basis points favorable to the fourth quarter of 2023. For the full year, our adjusted operating margin was 25.3%, which was a 110 basis point increase over 2023. Adjusted other income expense of $51 million for the quarter was $20 million higher than 2023, driven by a full quarter of higher interest expense related to our September 2024 debt issuance. For 2025, excluding the impact from the pending acquisition of Inari, we expect our full year other income and expense to be approximately $260 million, driven primarily by the full year impact of additional interest expense from our September 2024 debt issuance. Our fourth quarter and full year had an adjusted effective tax rate of 15.4% and 14.8%, respectively, reflecting the impact of geographic mix and certain discrete tax items. For 2025, we expect our full year effective tax rate to be in the range of 15%-16%. Focusing on the balance sheet, we ended the year with $4.5 billion of cash, marketable securities, and short-term investments. Total debt was approximately $13.6 billion and includes approximately $3 billion from our bond offerings in September 2024, of which a portion of the proceeds were used to pay down debt of $1.5 billion during the fourth quarter. Turning to cash flow, our full year 2024 cash from operations was $4.2 billion, an increase of $531 million from 2023, driven mainly by higher earnings and improvements in inventory and accounts payable. For 2025, we anticipate that capital spending will be in the range of $800 million-$850 million. We do not anticipate any share buybacks, and now I will provide full year 2025 guidance. Based on our momentum exiting 2024, a sustained level of procedural volumes, strong demand for our capital products, and our presence in healthy end markets, we expect organic net sales growth to be in the range of 8% to 9% for 2025 and expect adjusted net earnings per share to be in the range of $13.45 to $13.70 before considering the impact of Inari. This guidance assumes a full year adjusted operating margin of 26.3%, which is in line with our previous assertion to improve op margin to pre-COVID levels. Our sales guidance reflects our expectation that the full year impact of price is modestly favorable. Additionally, if foreign exchange rates hold near current levels, we anticipate sales will be unfavorably impacted by approximately 1% for the full year and that adjusted earnings per share will be negatively impacted in the range of $0.10-$0.15, both of which are reflected in our guidance. Compared to 2024, we will have one fewer selling day in the first quarter of 2025. The remaining quarters of this year will have the same number of selling days as 2024. Finally, while we do not provide quarterly guidance, we do expect the seasonality of our sales, op margin expansion, and related earnings to be similar to 2024. As it relates to the pending close of the Inari acquisition, we expect to fund the $4.9 billion purchase price through a mix of cash on hand and new debt and anticipate closing this transaction towards the end of February. For the approximately 10-month period ending in December 2025, we expect Inari to deliver approximately $590 million of sales on a constant currency basis and have a dilutive impact on adjusted op margin of 0 to 20 basis points and $0.20 to $0.30 on adjusted EPS. As it relates to the divestiture of our spine implants business, we expect that the impact of this transaction will be absorbed into the above guidance for net sales growth, adjusted operating margin, and adjusted EPS. With that, I will now open the call up for Q&A. At this time, we will open the floor for questions. If you'd like to ask a question, please press Star 5 on your telephone keypad. You may remove yourself at any time by pressing Star 5 again. We'd like to remind callers to please limit themselves to one question and one follow-up question so we can accommodate as many participants as possible. And we'll pause for just a moment. Okay. Our first question will come from Larry Biegelsen with Wells Fargo. Your line is now open. Please go ahead. Good afternoon. Thanks for taking the question. Congrats on a strong finish to the year. Kevin, just wanted to start on the spine sale. Just first, also congratulations to both Glenn and Preston. So Kevin, on the spine sale, just talk about why this was the right time, how much of that $700 million is going to VB, and just the economics of the deal, sale price, and how you're offsetting any dilution from the deal. And I had one follow-up. Thank you. Yeah, sure. Thanks, Larry. Why is now the time? As you know, we've been looking at this market for a long time, and we've been trying to make improvements in our spine business. We are excited about the enabling tech with Copilot and Mako spine, but fundamentally just have better opportunities to invest our funds in other businesses. The VB brothers have a lot of experience in spine. They're going to provide the follow-on innovation that's required in the implant side of the business. As you saw in the press release, we will be partnering together. So we will be providing the enabling tech. They will be providing the implants. The entire $700 million is expected to be divested to them. The remaining portions that we're keeping have been moved into other, the IVS into Neurocranial and the enabling technology being moved into other Orthopedics. It's just one of those things where we've moved into so many other faster-growing spaces, and this is really where we'd like to spend our time and our energy. It's, as you know, a very competitive market on the implant side of the business where we just haven't had the same degree of innovation that we've had in other parts of our portfolio. So this felt like the right time. We feel like we've got a really great partner. The business will be in good hands. Our employees will be in good hands, and so will our customers. Thanks. And then just to follow up on Inari, maybe for Andy or for Glenn, just talk about maybe some of the deal assumptions. By our math, the return on invested capital seems relatively low in year five. How do you see ROIC in five years, and when does this deal turn accretive? Thanks for taking the question. Yeah, Larry, thanks. We don't really guide on ROIC or talk about it too much, but we generally target to get back to WACC sometime between five and seven years. And I would say Inari fits squarely in that sort of model as we looked at our own modeling on this. We're super excited about their sales growth and the accretion of that to our sales growth, especially once we hit the one-year comparable mark on it. And honestly, from an operating income standpoint, we feel there are a lot of opportunities for us to partner with them. And obviously, we have the normal public company synergies that will be in our favor. And then when you work your way down to EPS, most of the impact will result from additional borrowings and the interest expense related to that in terms of the dilution we'll feel at the EPS level. Okay. Our next question will come from Robbie Marcus with JPMorgan. Your line is now open. Please go ahead. Oh, great. Congratulations on a really nice quarter. Glenn, I wish you the best in retirement. It was great working with you. Maybe a follow-up on Larry's questions and ask another way. And this is more of a P&L focus. It's really impressive that you could sell probably one of your lowest growth businesses and still be able to absorb it within the existing range that people expected and the guidance you provided on operating margins. So maybe just we got a good look at where your margin structure was and how you were planning to get there at the analyst day a little over a year ago. But as you sit here today, and there's a lot of moving pieces from that time to today, what is it that helps you get that 100-plus basis points expansion this year before Inari dilution, and what's still left to go afterwards? And any color into the building blocks would be really helpful. Yeah, sure. Thanks, Robbie. Gosh, there's so many opportunities still as I think through sort of how we look at our structure, how we look at our P&L, how we look at our manufacturing footprints. I would tell you that our GQO group is very excited about purchasing opportunities. We're very excited about expanding sort of our low-cost manufacturing footprint. We've recently opened up facilities in Poland. We have our Tijuana facility. There really are still a lot of robust opportunities as we think about how do we streamline. Moving on down the income statement, if I look at operating expenses, we really have scratched pretty hard the shared services sort of aspect of back office and transactional services, but I would say there is room to go for sure. We look at our worldwide facilities in Asia, in Poland, and in Costa Rica. First of all, there are some of the fastest-growing facilities we have. There are really some opportunities to even sort of push more transactional-type activities down to there. Even if we look at sort of leveraging R&D and using our India tech center more often, it just from a cost standpoint, we really have an opportunity to drive additional cost savings there too. And then honestly, a couple of my favorite ways to drive op margin, we are continuing to be very successful gaining price. And it's not just price in the U.S., it's price on a worldwide basis. And then lastly, the way our formula works, we get a lot of natural leverage just by growing sales 8%-9%. And that model will work, and that model will deliver what we need for 2025. Great. Maybe a follow-up. If I had to sum my takeaways coming out of our healthcare conference as it relates to your business from your competitors, it was that the ortho markets remain healthy and stable, volumes are robust, less negative pricing, and capital equipment markets remain healthy around the world. I wanted to see if you agree with that outlook. You always have great insights, and any other color if there's a difference in geography that you want to add. Thanks a lot. Hey, Robbie, it's Jason. I'll take this one. I would say well said. Across the board on the commentary there, I think we're very well aligned with that and feel really good as we enter 2025, really across all three of those. Our next question will come from the line of Travis Steed with Bank of America. Your line is now open. Please go ahead. Hey, thanks for taking the questions. And congrats, Preston. Look forward to working with you again. I wanted to ask about kind of the M&A. You guys used to have kind of five things on the list, and kind of checked one of those off of the Inari. So maybe kind of talk about, Kevin, some of your new prioritized list of focus areas for M&A. And is this going to be a period of kind of digestion, or is this going to be a period of continued M&A? And I assume that some of the proceeds from the spine business will help pay down debt so you can kind of get back on the offense on M&A sooner if that's the right read. Yeah. Listen, what I'd say is even with the debt to purchase Inari, even before any proceeds from spine, it takes our debt equity to around three times so that we still have capacity to continue to do tuck-in deals. And as a reminder, over the last 12 years, the majority of the deals we do are tuck-ins. And they can range inside. Most of them are kind of small, medium-sized. Occasionally, we do a large tuck-in, but we're still on offense and looking at acquisitions. I don't necessarily think that we'll do necessarily one as big as Inari in the near term. But the adjacencies continue to be the ones that I've talked about, peripheral vascular. Obviously, I've mentioned that in the past, and we're very excited to be able to consummate that deal. And the other spaces, like I've talked about urology, I've talked about neuromodulation, I've talked about soft tissue robotics, I've talked about healthcare IT. Those all remain very interesting spaces for us. But that's in addition to all of the tuck-ins. Every single business is out looking for deals. And you saw the seven that we did last year were all within our existing businesses. And that will continue to be the majority of the deals that we do. Those bring tremendous ROIC returns because we already have existing sales forces and call points. And once Inari is integrated into Stryker, we'll also continue to look within that peripheral space for follow-on acquisitions, just as we do with all our businesses. Great. Thank you. And I wanted to ask on the revenue guidance, 7%-9% there, kind of another year of above normal growth. And I guess five years now of above normal growth. It's probably kind of the new normal of higher growth. And so I wanted to kind of think about the sustainability of this kind of higher revenue. You've gotten LIFEPAK going and several of the pipeline products. So I want to just kind of talk about the sustainability of this growth rate that you've gotten and the confidence in the revenue guidance for 2025. Thank you. Yeah, thanks. Listen, just to clarify, the guidance was 8%-9% organic. And so on the low end, it's a little bit higher than it was last year. So we feel even less risk on the bottom end of the range. And look, we're feeling very bullish. If you look at all of our businesses, they all have robust pipelines, and they're constantly following on with innovations. Our commercial execution is extremely strong. I just spent a lot of time with our sales forces in the month of January at our kickoff meetings, and I could tell you the morale and the spirit has never been better. There are big impacts such as Pangea and LIFEPAK 35, those big launches, but there's a series of smaller product launches that are occurring across our portfolio, and so by now, I would hope everyone thinks and knows that it's durable. We're doing it year after year after year, and I don't see that slowing down anytime soon. Our next question will come from David Roman with Goldman Sachs. Your line is now open. Please go ahead. Thank you. Good afternoon, everybody. I wanted just to follow up maybe on a couple of strategic questions here. I think on the last call, you had cited that the acquisitions you had completed in 2024 were expected to contribute about $300 million this year. Can you maybe just give us an update on how that's progressing, how you're thinking about commercial strategy there, and any updates that you have observed since you've been able to close these deals? Yeah, sure. First of all, I'd tell you I'm extremely excited about the deals. All of the acquisitions are actually at or above the deal model. Kind of unusual for us. Normally, you'd have one or two that are a little bit below the model, but they've all taken off really, really well. And so that $300 million, we feel very confident about achieving or surpassing. The integrations, frankly, are very simple on these deals because they tuck into existing call points in existing business units of our company. In some cases, we've actually added some specialized sales forces, just additional specialized people. In the case of certainly of Vertos, we've added some additional sales feet on the street. And some of them came obviously with the company. We've decided to add some. But adding sales feet on the street is something we do every year. All of our businesses are constantly looking to split territories, to split sales forces or parts of sales forces. And we've created a number of small new sales forces across the company and continue to add salespeople. But it's quite an easy integration when you tuck it into an existing business with existing call points. And then maybe just a follow-up on the Mako Shoulder rollout. I think as your competitor is also coming out with the robotic shoulder solution as described, similarly, a measured and gradual rollout. Maybe you could just help us understand some of the dynamics in the shoulder market, how we should think about the addressable market here, the pace of adoption, if knees or hips was a good proxy, and how the robotic shoulder market should kind of evolve in your view over the next maybe one to three years? Listen, I'm extremely excited about Mako Shoulder. It's a very difficult procedure to do. And the harder the procedure is, the more the robot brings value. And in our case, we're doing bone preparation with haptics with our robot in a tight space. So the surgeon feedback, early feedback is extremely exciting, at least as exciting in knees, if not more. Now, it does require a lot of change management. We learned that through the knee launch, that sometimes you have to go a little slow at the beginning so that you can go fast later on. And so this year is going to be really getting the training protocols well defined and established, and we'll really start to see more acceleration in 2026 and beyond. So not much of an impact commercially, but our shoulder business doesn't really need it. It's growing strong double digits. It's been doing that since we acquired Wright Medical and had a fantastic year in 2024. And we'll have another great year in 2025, even without the impact of Mako. But this will take it to a whole other level. And as you know, as you've seen with knees, our robotic solution is clearly compelling and will be very differentiating. Our next question comes from the line of Pito Chickering with Deutsche Bank. Your line is now open. Please go ahead. Hey, good afternoon. And Glenn, thanks for all the years and Preston. Looking forward to working with you again. On the spine division, I know there's no color here on the economics around this transaction. But from a modeling perspective, with the deal closing in the first half of the year, how should we think about EPS seasonality this year? Does the transaction change the normal EPS seasonality of Stryker? Yeah, Pito. Yeah. Honestly, when we pull spine out, first of all, it's not really material to the overall numbers that we're delivering. And so I would say the seasonality that you saw in 2024 will generally carry forward to 2025 in terms of the cadence of sales, op margin expansion, and EPS. All right. Great. And then in 2024, Medical had a huge year. This never gets the same airtime as the other divisions. How should we think about growth there for 2025? And so what are the big growth drivers in Medical for this year? Thank you. Yeah. I've said this many times. I think it's the most underappreciated division within our company. And you should expect another year of double-digit growth in Medical. They have a tremendous number of growth drivers, tremendous momentum across whether it's Sage, emergency care, acute beds, wireless stretchers, Vocera. There's just a series of tremendous opportunities across the portfolio. So they're posting double digits on top of double-digit growth years, and I expect another year of double-digit growth in 2025. Our next question will come from the line of Vijay Kumar with Evercore ISI. Your line is now open. Please go ahead. Hey, guys. Thanks for taking my question, Glenn. Wishing you the best. Preston, congratulations as well. I guess my first question on just a guidance clarification. Inari is the maximum dilution impact here, 20 basis points. Glenn, is that what you're saying? And spine, I think the comment you made was spine will be absorbed in the current guidance. Does it mean the EPS of $13.45-$13.70, that's intact even without spine? You heard it right. Inari will be maximum 20 basis points dilutive to our op margin expansion. And spine will be absorbed in the EPS guidance that we gave of $13.45-$13.70. Understood. And then maybe one related question here on with spine below corporate margin, is that sort of aiding margins here? Inari, Kevin, this is a fairly quick deal close time. Sometimes we do have sales force disruption when deals are announced. But given the fairly quick deal turnaround time, I'm assuming that should be minimal here. Is that a fair assumption? And how did you guys get comfortable? I know there was some noise around a DOJ investigation. If you could just clarify on how you got comfortable, that would be helpful. Yeah. Hey, Vijay, I'm going to ask Andy to answer that since he's here in the room with us. Go ahead, Andy. Sure, Vijay. Yeah. The timing of the deal close, we do anticipate, as noted, to be by the end of February. And we got pretty comfortable around that based on the regulatory filings and other customary closing conditions. And we feel like we're going to be in pretty good shape there. Then secondarily to your question around the CID, of course, that was an area where we did go deep into and gaining our understanding of what the risk was with the CID. And as you see, of course, we went through with the transaction. Our next question comes from the line of Matthew O'Brien with Piper Sandler. Your line is now open. Please go ahead. Afternoon. Thanks for taking that question. Maybe this one is for Andy specifically, but just based on my math of the 560, thinking about the annual contribution from Inari, it looks like it's about $670 million. So roughly about $40-$50 million of lost sales, I think that you're factoring in versus what the Street had been modeling. So that's about 11% growth. So kind of well below market. Andy, do you think you can get this business back to market growth, or do you need to fold in other technologies to be able to do that type of growth in the future, be it aspiration, etc.? Hey, let me be really clear. This is only for 10 months' worth of sales. We are assuming high double-digit growth in this business. So not very far off from the growth rate they have. We are not assuming any falloff. And you can follow up with Jason afterwards. It was 590, not 560. And it's only for 10 months of the year, not 12 months of the year. So we are not assuming a falloff. We think the sales force is going to stay very engaged. There isn't any overlap with our business. So we're not going to have the sales force integration challenges that we have had with overlap deals. This plugs right alongside our existing business. And we plan to continue to make this business sing just the way they have as an independent company. Got it. Got it. Thanks. I'll figure out how to do math one of these days. And then, Kevin, for you specifically, I know it's early in the year, but just the top line guide of 8%-9%, and you're trying to be, I'm sure, somewhat conservative. But just getting even to the low end of that range, just given the momentum and trauma in the extremities looks unbelievably good. MedSurg, you just talked about double digits, still well above average on the knee side of things. I just guess, what would get you down to the 8%-ish range versus midpoint or even higher, just given, again, all the momentum that we see in the business? Yeah. Listen, I feel really good about the business. Look, it's early in the year. And so the activity levels, procedure levels, capital, we have good visibility, at least for the first six, seven, eight months, but that's not a full year. And things can change. So obviously, every quarter, we're going to continue to update our guidance. And last year, you saw us steadily move up our guidance. I'm not going to predict what will happen this year, but assume that we're going to continue to be playing offense. And we're going to continue to launch products. Those have to continue to go smoothly as they have in the past. And if everything goes to plan, we could expect another very strong year towards the upper end of our guidance or potentially moving it up. But certainly, don't feel risk on the downside. And I'm hopeful that if we continue the momentum the way it is, that we'll be able to deliver above where we're currently guiding. But remains to be seen. Our next question comes from Shagun Singh with RBC. Your line is now open. Please go ahead. Great. Thank you so much. And congratulations to both Glenn and Preston here. I was just wondering if we should expect any shift in priorities given this transition. And then, Kevin, a question for you on the LRP. Your algorithm, growth algorithm, has been 5% weighted average market growth, plus another 200-300 basis points of outperformance gets you to 7%-8%. You have exceeded those levels in recent years, including 2024. And you've made some deals here as well. So how should we think about that weighted average market growth going forward? And then just similarly on margins, you guys had previously said at least 30 basis points annually beyond 2025. How do you think about peak levels? Thank you for taking the questions. Yeah. Thanks, Shagun. We're going to have an analyst day later this year. And so we'll update at that time kind of the growth algorithm for the future years beyond 2025. Clearly, we're moving into faster-growing markets. So that weighted average market growth rate is moving up as we increase our exposure to faster-growing end markets. And as it relates to operating margin expansion, you saw we had a terrific year in 2024. We're planning on another strong year. We believe we have this operating margin power in the company, which is why we're absorbing spine, which is why even for the Inari acquisition, we're not planning to give up much in the way of dilution at the operating margin level. But in terms of committing beyond that, I think we'll do that later on in the year at the analyst day. Oh, sorry. As it relates to the second part of your question, sorry, there were many parts to your question. As it relates to priorities, I would say with me sitting in the chair here as CEO, with Preston having been in the company both in the IR capacity and as the head of finance for Orthopedics and Spine, you shouldn't expect any change in terms of our priorities. Okay. Our next question will come from Matt Miksic with Barclays. Your line is now open. Please go ahead. Hey, great. Thanks for taking the question. And congrats to everyone who's moving in and out of these positions. Preston, looking forward to working with you again, as everyone has said. I know the conversation has been around spine. There were a ton of questions. I don't think anybody saw this coming, but it does make a lot of sense for what it's worth. I just had one question maybe around some of the other businesses that have been doing so well with these many product launches that we spent a good part of last year talking about. So camera, the insufflator, even things like, I don't know, powered instruments and waste management. Just the basic question is, these are all punching kind of above double digits. How many, maybe if you could tick through any of them that are going to start to kind of hit the other side of these refresh and product cycles by the end of the year? Or do all these carry into 2026? Any kind of color you could give on sustainability would be great. And I have one quick follow-up. Yeah. Yeah. Thanks. Thanks, Matt. As you rightly say, we have a lot of businesses that are really firing on all cylinders. Thanks for mentioning the camera. Because I think a year ago at this time, there was a lot of speculation that we would be impacted by the DR5. And that's clearly not the case. Looking at our tremendous performance in cameras, there's plenty of room for both companies to grow. The way we do our launches is just before you start to see the business start to peter out of the new product as it comes on the scene. And so we have that all locked and loaded. The pipelines are still. We're still investing healthy rates in R&D. So you shouldn't expect really any material slowdown in any of those businesses in 2025. And we will restock the funnel and be able to launch products before you start to see that. In the old days of Stryker, if you go back 10 years, you'd sort of have a bit of a gap sometimes. And in that gap year, you would have lower growth. But as you've noticed in the last five, six, seven years, before the product starts to flag in terms of its growth, another System 8 goes to System 9, will go to System 10. We have the R&D products teed up to be able to insulate against that. So I'm feeling very good about 2025. And then, again, we'll have an analyst day later in the year, and we'll talk about the outlook in the future. Great. And then just a quick follow-up on the shoulder. I know focus on the robot as being an important catalyst here. And one of your competitors is out there with the robot. Could you give us a sense because it's not just the implants and the robot, right? I mean, there's a fair amount of other enabling technology. Could you give us a sense of maybe how that's contributing to growth? What the uptake or adoption has been like there and what other enabling technology solutions besides the robot you see as contributing to growth for shoulder in the next, say, I don't know, 12-18 months? Yeah, well, first of all, we have an incredible ecosystem with our Blueprint software and market-leading implants, like absolutely terrific implants, stemless, short stem, anatomic, reverse, perform humeral system, which is totally modern and outstanding. And Blueprint provides AI guidance to the surgeon that actually presents the surgical plan with which type of implant should be implemented. And that Blueprint software has been integrated with the robot. So the same software that the surgeons used to using to plan their procedure will be the same software they're using on Mako. And so that has been the formula for the Tornier system under Wright Medical and now under Stryker to have market-leading growth for years. And we plan to continue that progress forward. And Mako is just an added benefit, but it hasn't been like we've needed the robot. And initially, our robot's going to start off with reverse, which is about two-thirds of the procedure. So by far, the most procedures are reverse. And then eventually, we move to other parts of the procedure. But as we saw with hips and knees, not all robots are equal. And we love our Mako Shoulder application. And you'll start to hear surgeon feedback about it. We'll be showing it at AAOS. If you're at AAOS, you'll get a chance to see it. It's really compelling. We think it's going to be very powerful. But again, it's not as if the shoulder business really even needs this because of the high growth that they already have with market-leading implants and Blueprint software, which is the best-in-class software system to navigate and plan your shoulder. And not to mention that we have Shoulder iD, which is a custom patient-matched glenoid. Glenoid, as you know, is the trickiest part of the anatomy. And we are actually just starting to expand that personalized solution, which surgeons find absolutely fantastic, saves them time. You don't have to put in augments in the shoulder. So there's a series of other product launches that we have that are pretty exciting. And longer term, I can imagine mixed reality will play into this. But that's sort of looking at 2026, 2027, and beyond. Our next question will come from Mike Matson with Needham & Company, Inc. Your line is now open. Please go ahead. Yeah. Thanks. So with the spine, the divestiture, I just wanted to ask about how the Mako and enabling technologies partnership will sort of work. I know one of your competitors tried to do something similar when they spun out their spine business, and it didn't really seem to work in the end. And is there still the same type of revenue opportunity here from the Mako spine robot? Yeah. Listen, the Mako spine robot's going to be compelling because it's Mako. And the brand is extremely strong. And the initial cases we've done have gone very well. The surgeons who are using our existing spine implants will now be obviously served by similar salespeople that'll be part of the VB Spine business. So there won't be a lot of change in that respect. It'll just be the same rep in the operating room using Mako and the same implants that they've been using today, and then the VB Spine team will obviously go out and try to attract other surgeons to join the business, so we already operated in two different worlds. We had capital salespeople providing Mako and our Makoplasty specialists, and then we had the implant business, so instead of that being Stryker Spine, it's now VB Spine, so it's not really for the customer a big difference. We have a little bit more work to do because it's a third party, so when we're doing contracts, we have to contract together with a third party, but I'm not expecting it to be really a big difference versus what we have. What does change is we're not going to be investing in all the innovation on implants and having to deal with the management of the implant business, which, to be frank, we have not done a great job over the past 10, 12 years. It's a tough competitive market, which the VB brothers know very well. They've been in this business a long time. They know this business. And I think they're going to be laser-focused on it. Whereas for us, we have a lot of other areas of investment that we put a bit more focus on. But to the customer, in the short term at least, it's not going to be much of an impact. And what we thought we could do with Mako spine in terms of the revenue isn't much different with this partner. They're going to be exclusive at least for the first few years. And then we'll see what happens beyond that, whether it stays exclusive or whether it becomes a more open system. But I'm hoping that it stays exclusive and that they do really, really well and we do well alongside. Okay. Got it. Thanks. And then just in terms of, I know you mentioned that you've got a plant in Mexico. There's talk of potential tariffs on Mexico and Canada. So how much of your manufacturing is coming from either of those two countries? And how much flexibility do you have to move production elsewhere if we do end up seeing some tariffs there this weekend? Yeah. Yeah. It's a good question. I think, first of all, just you got to keep in mind the scale here. We have roughly 40 manufacturing plants around the world, and we have one in Mexico. It does assembly of some of our products. So right now, we are looking at this closely. We're following the discussions. It's a little early to really evaluate what the possibility of that might be and the impact to us or even maybe the potential follow-on impact to customers. So right now, I would say we're, like most companies, especially medical companies, that may be excluded at some level from a certain level of tariffs. We're watching and sort of seeing which way this develops. But keep in mind, it's one plant out of 40. Our next question will come from the line of Caitlin Cronin with Canaccord Genuity. Your line is now open. Please go ahead. Hey, congrats on a great quarter and congrats to Glenn and Preston as well. I guess just to start off with these new Mako launches in spine and shoulder, have you seen any momentum increase interest from hospitals and ASCs about the excitement of just having a one-stop shop for the Mako solution, as you've kind of touched on before? Yeah. It's a bit early still, right? We're just kind of in limited launch on both of these. And we're gaining experience. And we're not out actively, certainly on shoulder, not actively promoting it in ASCs yet. We're going to stay in a limited number of sites to make sure we get all our training protocols done. There is excitement. The Mako brand is a strong brand, certainly because of our success with knees and hips. And so I do expect that we're going to be asked about it. But it's early days still. I would say stay tuned. We'll update you in future quarters as the launches proceed. Spine will move a little bit more quickly than shoulder. There's less change management involved for the surgeon. So that'll move to a quicker launch. So we'll probably be able to tell you more about spine probably at the end of Q3. Got it. Thanks. And then just a strong trauma extremities number. You didn't really mention foot and ankle in the commentary. How did that business fare in the Q4 and any commentary on the market environment going into 2025? Yeah. You recall, the first couple of quarters of the year, the foot and ankle market was very soft. It did start picking up kind of around September, and fourth quarter certainly was better for the market overall, and our business did improve. But the real story around an unbelievable fourth quarter for trauma extremities, it was really powered by our shoulder business and our core trauma. Core trauma business had an exceptional quarter. And it was partly Pangea, but not just Pangea, just amazing sales force execution in that business. And Pangea has created a halo impact around the entire business. And I expect trauma extremities to have a terrific year again in 2025. Our next question comes from the line of Richard Newitter with Truist Securities. Your line is now open. Please go ahead. Hi. Thanks for taking the questions and congrats, Preston, and good luck, Glenn. Just going back to the CapEx environment question, I think someone asked earlier. I'm just curious. You guys obviously have great insight into conversations at the hospital C-suite level. Just with all the rhetoric going on out there about potential healthcare policy changes coming, some of the uncertainty that must be brewing with some of your customers. I'm just curious. Are you starting to see maybe not for the 2025 fiscal years and budgets, but are there any different behavior changes that are going on? Or how are your customers, if at all, expressing any of that potential emerging anxiety? Hey, Rich, it's Jason. I won't try to speculate on any policy potentially coming in the future. But what I would say is similar to what I said earlier on the call, which is, as we look at kind of the capital environment as we ended 2024 and, frankly, early days here in 2025, very positive for us. We feel good about the environment, certainly, and don't have any reason to believe as we go throughout this year it'd be any different at this point. Okay. That's very encouraging to hear. And maybe just one more on our end of process. We all had access to the proxy, and I think I read it right. But it looked like you guys got access to the financials and whatnot in early December. It feels like a pretty quick turnaround to diligence. I guess, one, was I reading that right? And can you give any color on how much work had been done prior to that or how you got comfortable with the diligence on this end market and the company so fast? Yeah. Listen, it's a publicly traded company. That is a very typical due diligence period you have for publicly traded companies. There's a lot of information that was publicly available. And we had done our homework, frankly, prior to the start of this. As you know, I've mentioned peripheral vascular many, many times. So we were absolutely prepared and done all of our homework on everything public. And then when we got a chance to go in and look at things and go into our due diligence, we knew exactly where to look, what to look for, including the R&D pipeline, and felt very good about what we saw with the team that we sent there. So this is not atypical for a public company deal. And we feel like we had a really sufficient amount of due diligence to feel comfortable moving forward. Our next question comes from the line of Josh Jennings with TD Cowen. Your line is now open. Please go ahead. Hi. Good evening. Thanks so much. And congrats to Glenn and Preston. Kevin, I was hoping to just touch on the continued kind of build-out of the ASC infrastructure in the U.S. It's been a tailwind, Stryker's best positioned. I think most think about procedure volume increases as being the biggest boost. But many of your businesses are levered to this continuing year-over-year increase in the number of ASCs in the U.S. So I guess the question is really, maybe one, what ending are we in in this ASC infrastructure build-out in the U.S.? And two, just help us think about which businesses, because I think there are a lot, maybe it's too long to answer, but that are benefiting from this tailwind, and how long do you expect this to last? Yeah. Listen, I still think we're in early innings. And it's very exciting for us at Stryker. I love this trend because we have many businesses that play in the ASC. And most of the deals that we do, especially new construction and builds and big renovations, involve at least six of our business units and sometimes more, which is really exciting. Obviously, the ones that you think about automatically are hips and knees, but it also involves our Orthopedic instruments. It can involve foot and ankle. It always involves sports medicine, communications, booms and lights. Sometimes you have stretchers. There's a suite of businesses, and every one is customized. Every ASC deal is unique because the number of RRs varies, and the types of procedures that they choose to do also varies. Normally, you always have sports. You have hips, and you have knees, and then you have potentially other procedures around that Interventional Spine and on and on. We love the way things are moving, even ENT. But what I'd say is, if you think about just hips and knees as kind of like the sort of the biggest change that's occurred in the last four or five years, in this fourth quarter, we hit a high for both hips and knees in the U.S. ASC market. Knees, there were 17% of our knees were done in the ASC and 14% of our hips. And that's just been, I'll call it a steady climb quarter after quarter. It's not sort of inflecting, but it's just a steady increase. And I think the only gating factor is construction of new ASCs, which will take time. This is not something that I see kind of changing the ramp of the curve, is just going to continue kind of on its current linear trajectory. I don't think it's going to inflect because capacity just isn't easy to bring on stream in large, large, large quantity. So I think it'll just be a continuation. And I don't see an end in sight because patients have a great experience. The surgeons love it. And healthy people should be going to these places to get procedures and don't have a risk of getting and contracting illnesses when they're there. And sick people go to hospitals, and healthier people are going to go to ASC. So I don't see this slowing down, but it'll be a gradual progression over time. Appreciate that. And then just to follow up on the answer to the acquisition strategy post-Inari, getting that weighted average market growth rate higher, there are many high-growth cardiovascular segments, and you're now in peripheral vascular. Should we consider this kind of initial thrust into the peripheral vascular kind of opening the door to other high-growth cardiovascular sectors as well for Stryker? Thanks again for taking the questions. Yeah. Thanks for the question. At least initially, let's integrate this, and we'll look to probably add within the peripheral space. Beyond that, we'll see longer term. But I don't expect that we'll, in the near term, kind of make a jump into cardiovascular. I think we have to do our homework here, get this integrated, and frankly, build around these call points that we're in right now. There's a lot more room within even peripheral vascular for them to play. And those emerging technologies are really exciting. We want to light those on fire and be able to realize those businesses. And we also have a lot of other mouths to feed across Stryker. A lot of businesses that are sort of spinning up deals. And so I think we're going to pay attention to those at least for the rest of this year. Our next question will come from the line of Danielle Antalffy with UBS. Your line is now open. Please go ahead. Hey, good afternoon, guys. Thanks so much for taking the question. And Glenn, congrats to you. Enjoy retirement, Preston. Really looking forward to working with you again. Just a question on R&D and productivity there. I mean, you saw pretty healthy growth in R&D in 2024. I mean, this plays into the super cycle of new products you have. And it also helps on the pricing front. I mean, how do we think about R&D spend going forward? Appreciate you guys for 2025. You've given us some goalposts there. But just at a high level, what you're seeing from an R&D productivity perspective and really how the focus might be changing there, if at all, to ensure you continue to get at least some modest price benefit and sustain this level of growth based on what is a very steady cadence of new product launches. Thanks so much. Yeah. Yeah. Thanks, Danielle. And honestly, thanks for your question on R&D. It gives us a chance to talk about the amazing job that our teams are doing in R&D and lining up pipelines of products and new product launches and feature enhancements. And so honestly, that innovation engine is a giant engine of Stryker. And we generally target anywhere between 6%-7% of sales as sort of a rough number to make sure that we're investing in R&D. It receives a very high priority in terms of as we go through our budgeting or our strategic planning process. We don't plan on backing down from that in any which way. We're very excited to take on the innovation of Inari and have those teams fold into our current innovation engine and feel like there'll be great synergies with our neurovascular business on there. So honestly, I don't see that strategy really changing just in terms of the kind of spend we prioritize there. I think we're looking at where we look to drive better efficiencies might be where we're doing the R&D or building up centers of excellence around software programming or AI or digital or any of those things. But honestly, I think in the 6%-7% range, I think that's probably where you'll continue to see us stay. Thank you. Our final question comes from the line of Michael Polark with Wolfe Research. Your line is now open. Please go ahead. Good afternoon. I just have one final follow-up on the guidance, the organic revenue growth guidance as it relates to the spine. So I just want to be very clear. The full year for the full company is guided 8% to 9%. You're saying that includes spine, which if I'm doing math, assuming the 1H close it's kind of 150 to 250 basis points of impact. So am I to look at the 8 and a half, say, plus 2 is 10 and a half as real kind of remaining core organic revenue growth guidance for 2025? Thank you. Yeah. Hi, Michael. I think this is something maybe you can follow up with Jason offline. The spine, our 8%-9% organic will get some benefit when spine is divested because spine is growing at a lower rate. But it's pretty small, the impact on the overall Stryker business. And Jason can follow up with you offline on that. But that'll give us a slight benefit, probably not that similar to the headwind we're going to get by having one less day in next year than we do this year. So those two kind of more or less offset. So the 8%-9% is a pretty good guide, a pretty healthy guide. And spine doesn't give us this massive benefit just given its size. But again, Jason can follow up with you offline on that. There are no further questions. I'll now turn the call over to Kevin Lobo for closing remarks. Well, thank you all for joining our call. I want to thank Glenn once again for great nine years and also for building a great pipeline of talent in finance. We're obviously Preston, but the entire finance organization. We have terrific people all over the company, just as we do in our commercial organizations. We've, over time, built extremely strong functions at Stryker that support our businesses and line up behind our business to help them succeed. And we look forward to sharing our Q1 results with you in early May. Thank you.