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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D.C. 20549 FORM 10 - K □ Annual Report Pursuant to Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 for the fiscal year ended December 31 , 2020 or Transition Report Pursuant to Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 Commission file number 1-8002 Delaware ( State of incorporation ) THERMO FISHER SCIENTIFIC INC . ( Exact name of Registrant as specified in its charter ) 168 Third Avenue Waltham , Massachusetts 02451 ( Address of principal executive offices ) ( Zip Code ) Registrant's telephone number , including area code : ( 781 ) 622-1000 Securities registered pursuant to Section 12 ( b ) of the Act : Trading Symbol ( s ) Title of each class Common Stock , $ 1.00 par value 2.150 % Notes due 2022 0.750 % Notes due 2024 0.125 % Notes due 2025 2.000 % Notes due 2025 1.400 % Notes due 2026 1.450 % Notes due 2027 1.750 % Notes due 2027 0.500 % Notes due 2028 1.375 % Notes due 2028 1.950 % Notes due 2029 0.875 % Notes due 2031 2.375 % Notes due 2032 2.875 % Notes due 2037 1.500 % Notes due 2039 1.875 % Notes due 2049 ΤΜΟ TMO 22A TMO 24A TMO 25B TMO 25 TMO 26A TMO 27 TMO 27B TMO 28A TMO 28 TMO 29 TMO 31 TMO 32 TMO 37 TMO 39 TMO 49 04-2209186 ( I.R.S. Employer Identification No. ) Name of each exchange on which registered New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange New York Stock Exchange Securities registered pursuant to Section 12 ( g ) of the Act : None Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Yes No Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or 15 ( d ) of the Act . Yes □ No - Indicate by check mark whether the Registrant ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes No Indicate by check mark whether the Registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T during the preceding 12 months . Yes No Indicate by check mark whether the Registrant is a large accelerated filer , an accelerated filer , a non - accelerated filer , a smaller reporting company or an emerging growth company . See the definitions of " large accelerated filer , ” “ accelerated filer , ” “ smaller reporting company ” and “ emerging growth company " in Rule 12b - 2 of the Exchange Act . Large accelerated filer Accelerated filer company Non - accelerated filer Smaller reporting Emerging growth company □ Indicate by check mark whether the registrant has filed a report on and attestation to its management's assessment of the effectiveness of its internal control over financial reporting under Section 404 ( b ) of the Sarbanes - Oxley Act ( 15 U.S.C. 7262 ( b ) ) by the registered public accounting firm that prepared or issued its audit report . Indicate by check mark whether the registrant is a shell company ( as defined in Rule 12b - 2 of the Exchange Act ) . Yes No As of June 26 , 2020 , the aggregate market value of the voting stock held by nonaffiliates of the Registrant was approximately $ 138,639,543,000 ( based on the last reported sale of common stock on the New York Stock Exchange Composite Tape reporting system on June 26 , 2020 ) . As of February 6 , 2021 , the Registrant had 393,793,362 shares of Common Stock outstanding . DOCUMENTS INCORPORATED BY REFERENCE Sections of Thermo Fisher's definitive Proxy Statement for the 2021 Annual Meeting of Shareholders are incorporated by reference into Parts II and III of this report .