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( Mark One ) ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31 , 2020 OR UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON , DC 20549 TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number : 001-35890 Delaware ( State or other jurisdiction of incorporation or organization ) Title of Each Class Common Stock , $ 0.001 par value FORM 10 - K 110 Miller Avenue , Suite 100 Ann Arbor , Michigan ( Address of principal executive offices ) " Millendo Therapeutics , Inc. ( Exact Name of Registrant as Specified in its Charter ) X Registrant's telephone number , including area code : ( 734 ) 845-9000 Securities registered pursuant to Section 12 ( b ) of the Act : Trading Symbol ( s ) MLND Securities registered pursuant to Section 12 ( g ) of the Act : None 45-1472564 ( I.R.S. Employer Identification No. ) Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Yes No x Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or 15 ( d ) of the Act . Yes No x Indicate by check mark whether the registrant ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months ( or for such shorter period that the registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes x No Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( § 232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the registrant was required to submit ) . Yes x No Indicate by check mark whether the registrant is a large accelerated filer , an accelerated filer , a non - accelerated filer , smaller reporting company , or an emerging growth company . See the definitions of “ large accelerated filer , ” “ accelerated filer , ” “ smaller reporting company , ” and “ emerging growth company " in Rule 12b - 2 of the Exchange Act . Large accelerated filer Non - accelerated filer 48104 ( Zip Code ) Indicate by check mark whether the registrant is a shell company ( as defined in Rule 12b - 2 of the Exchange Act ) . Yes Name of Each Exchange on which Registered The Nasdaq Stock Market , LLC As of March 15 , 2021 , the registrant had 19,043,034 shares of common stock , $ 0.001 par value per share , outstanding . If an emerging growth company , indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13 ( a ) of the Exchange Act . " DOCUMENTS INCORPORATED BY REFERENCE Accelerated filer Smaller reporting company Emerging growth company Indicated by check mark whether the registrant has filed a report on and attestation to its management's assessment of the effectiveness of its internal control over financial reporting under Section 404 ( b ) of the Sarbanes - Oxley Act ( 15 U.S.C 7262 ( b ) ) by the registered public accounting firm that prepared or issued its audit report . Yes No X ■ П No X The aggregate market value of the voting and non - voting common equity of the registrant held by non - affiliates as of June 30 , 2020 ( the last business day of the registrant's most recently completed second fiscal quarter ) , based on a closing price of $ 1.76 per share of the registrant's common stock as reported on The Nasdaq Capital Market on June 30 , 2020 , was approximately $ 33.3 million . For purposes of this computation , all officers , directors , and 10 % beneficial owners of the registrant are deemed to be affiliates . Such determination should not be deemed to be an admission that such officers , directors or 10 % beneficial owners are , in fact , affiliates of the registrant .