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Table of Contents ( Mark One ) П UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington , D.C. 20549 ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31 , 2020 or TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from FORM 10 - K Delaware ( State or Other Jurisdiction of Incorporation or Organization ) 955 Chesterbrook Blvd. , Suite 110 , Chesterbrook , PA ( Address of Principal Executive Offices ) Commission File Number 001-36193 Trevena , Inc. ( Exact Name of Registrant as Specified in Its Charter ) Securities registered pursuant to Section 12 ( b ) of the Act : Registrant's telephone number , including area code : ( 610 ) 354-8840 Title of each class Common Stock , par value $ 0.001 per share Securities registered pursuant to Section 12 ( g ) of the Act : None to Trading Symbol ( s ) TRVN 26-1469215 ( I.R.S. Employer Identification No. ) 19087 ( Zip Code ) Accelerated filer Name of each exchange on which registered The Nasdaq Stock Market LLC Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Yes No Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15 ( d ) of the Act . Yes □ No > Indicate by check mark whether the registrant ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months ( or for such shorter period that the registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes No Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( § 232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the registrant was required to submit such files ) . Yes > No Indica by chec nark whether the registrant is a large accelerated filer , an accelerat filer , a non - accelerated filer , or a smaller reporting company . See the definitions of “ large accelerated filer , ” “ accelerated filer , ” “ smaller reporting company ” and “ emerging growth company " in Rule 12b - 2 of the Exchange Act .: Large accelerated filer Emerging growth company If an emerging growth company , indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13 ( a ) of the Exchange Act . Non - accelerated filer > Smaller reporting company Indicate by check mark whether the registrant has filed a report on and attestation to its management's assessment of the effectiveness of its internal control over financial reporting under Section 404 ( b ) of the Sarbanes - Oxley Act ( 15 U.S.C. 7262 ( b ) ) by the registered public accounting firm that prepared or issued its audit report . □ Indicate by check mark whether the registrant is a shell company ( as defined in Rule 12b - 2 of the Exchange Act ) . Yes No The aggregate market value of the voting stock held by non - affiliates of the registrant , as of June 30 , 2020 , the last business day of the registrant's most recently completed second fiscal quarter , was approximately $ 189.4 million . Such aggregate market value was computed by reference to the closing price of the Common Stock as reported on the Nasdaq Stock Market LLC on June 30 , 2020. For purposes of making this calculation only , the registrant has defined affiliates as including only directors and executive officers and stockholders holding greater than 10 % of the voting stock of the registrant as of June 30 , 2020 . The number of shares of the registrant's Common Stock outstanding as of March 5 , 2021 was 161,273,660 . DOCUMENTS INCORPORATED BY REFERENCE Portions of the registrant's definitive proxy statement for its 2021 annual meeting of stockholders to be filed pursuant to Regulation 14A with the Securities and Exchange Commission not later than 120 days after the registrant's fiscal year ended December 31 , 2020 are incorporated by reference into Part III of this Form 10 - K .