Do we dance on the table? Good morning, ladies and gentlemen. Thank you for standing by. Welcome to VolitionRx Limited's Q1 of 2023 earnings conference call. During today's presentation, all parties will be in listen-only mode. Following the presentation, the conference call will be opened for questions. If you have a question, please press the star key followed by the number 1 on your touch-tone phone. If you'd like to withdraw your question, please press the star key followed by the number 2. If you're using speaker equipment, it may be necessary to lift the handset before making your selection. This conference is being recorded today, May 11th, 2023. I'd now like to turn the conference over to Scott Powell, Executive Vice President of Investor Relations. Welcome everyone to today's earnings conference call for VolitionRx Limited. This call will cover Volition's financial and operating results for the Q1 of 2023, along with a discussion of our recent activities and key upcoming milestones. Following our prepared remarks, we will open the conference call to a question-and-answer session. Also on our call today, Mr. Cameron Reynolds, President and Group Chief Executive Officer, Dr. Tom Butera, Chief Executive Officer of our Volition Veterinary subsidiary, and Mr. Terig Hughes, Group Chief Financial Officer. Before we begin, I'd like to remind everyone that some of the information discussed on this conference call will include forward-looking statements covered under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These statements are based on our beliefs as well as assumptions we have used based upon information currently available to us. Because these statements reflect our current views concerning future events, these statements involve risks, uncertainties, and assumptions. Actual future results may vary significantly based on a number of factors that may cause the actual results or events to be materially different from future results, performance, or achievements expressed or implied by these statements. We have identified various risk factors associated with our operations in our most recent annual report on Form 10-K, quarterly reports on Form 10-Q, and other filings with the Securities and Exchange Commission. We do not undertake an obligation to update any forward-looking statements made during the course of this call. I would now like to turn the call over to our President and Chief Executive Officer, Mr. Cameron Reynolds. Cameron. Thanks, Scott. Thank you everyone for joining Volition's Q1 2023 earnings call today. We really appreciate your time, given this is the busy earnings call season. We will commence the call with a financial report from our Group Chief Financial Officer, Terig Hughes, before moving on to Dr. Tom Butera, Chief Executive Officer of Volition Veterinary, for an update on the rollout of Nu.Q Vet by our global supply and licensing agreements. Finally, I will provide an update on the great progress the team have been making with regards to another of our key pillars, Nu.Q NETs, and further highlights from the Q1. Without further ado, I'll hand across to Terig the financial report. Terig. Thanks very much, Cameron. Thank you everyone for joining our earnings call today. I'll now provide a summary of the key financial results for the quarter ended March 31, 2023. We ended the quarter with cash and cash equivalents of approximately $10 million compared with $10.9 million at the end of 2022. In February, we received approximately $8 million in net proceeds from a public offering of our common stock before deducting offering expenses payable by the company. We expect to receive a further $13 million in milestone payments from Heska Corporation and additional funding, including non-dilutive funding from three Belgian agencies in the coming months. Net cash used in operating activities during the quarter was approximately $8.7 million and reflected the ramp-up in our U.S. clinical trial activities. Moving on to the P&L. While we continue to manage our costs carefully, as expected, the overall level of expenditure has increased in comparison to the Q1 of 2022. Total operating expenses for the quarter were $9.2 million compared to $7.8 million for the Q1 of 2022. This increase was primarily the result of increased expenditure in the research and development function, mainly reflecting the costs of our U.S. clinical trials, which added $1.1 million to the cost in the quarter. Revenue for the Nu.Q Vet cancer test grew by 381% to $124,000, reflecting sales of the reference kit through our agreements with both IDEXX and Heska. Total revenue reported in the Q1 of 2023 was approximately $150,000 versus $114,000 for the Q1 of the prior year. Net loss for the quarter was $8.9 million compared to $7.7 million for the three months ended March 31st, 2022, again, reflecting the increased costs of our U.S. clinical trial activities. We discussed on the previous call and plan to cover in some detail at our capital markets event later today. Given the product range we expect we can develop from our proprietary Nucleosomics platform, we believe our addressable markets are very significant, most notably in the short term with Nu.Q Vet and Nu.Q NET, we look forward to updating you in due course on our progress in accessing these opportunities. With that, I'm delighted to hand over to Dr. Tom Butera, who will provide further detail regarding the exciting Q1 for the Volition Veterinary team. Tom? Thanks very much, Terig. Good morning, everybody. The Q1 of 2023 has been pivotal for Volition. Our Nu.Q Vet cancer test is now available through IDEXX's reference lab network. A global leader in pet healthcare innovation, IDEXX launched our test in the U.S. at the world's largest veterinary conference, VMX, earlier this year. Is now looking to roll it out to other countries. This is an incredible step forward for us as we continue to commercialize our transformational Nu.Q technology with the companion animal healthcare sector. Our test is also now available as the Heska Nu.Q Canine Cancer Screen and Monitor test through Heska's veterinary diagnostic laboratory and for pre-order at the point of care. Available in the coming months, it will be the first time that our Nu.Q technology will be used outside of centralized laboratory testing and will provide veterinarians with rapid, accurate, low-cost, and easy-to-use on-site testing in the veterinary clinic to support their clinical decision making. We are absolutely thrilled to be working with IDEXX and Heska, two global industry leaders. I could not be happier that the Nu.Q Vet cancer test is now available in the mainstream mass market in the United States. There are approximately 84 million pet dogs in the United States. About 50% of US households bring their dog to the vet annually for a health exam. We believe that this provides a significant opportunity for us to introduce the Nu.Q Vet cancer test as an accessible and affordable screen for senior dogs and at-risk breeds to aid in early detection and improve outcomes. It is a huge step forward and fantastic news for veterinarians, pet owners, and their pets. I am also happy to report that Professor Heather Wilson-Robles' peer-reviewed paper on the use of the Nu.Q Vet cancer test for monitoring the disease was published yesterday in PLOS ONE. The publishing of this monitoring paper achieves another very important milestone, and we believe has the potential to open up a considerable new market for our existing Nu.Q Vet cancer test. As discussed in the paper, findings from the study show that nucleosome concentrations can be a useful tool for treatment monitoring and disease progression in dogs with hematopoietic cancers, such as lymphoma. While veterinarians can already use our Nu.Q Vet cancer test as a reliable and affordable screening tool for dogs with increased risk of developing cancer, this new research demonstrates another potentially significant utility of the test as an innovative monitoring tool for canine lymphoma management, providing actionable information and helping guide treatment decisions. You can hear more about the monitoring study and findings from Professor Heather Wilson-Robles at our Capital Markets Day event later this afternoon. In wrapping up and looking ahead, we continue to pursue commercial deals at a global, regional, and local level to ensure global distribution of the Nu.Q Vet cancer test. We are also continuing to develop our feline product and extend our Nu.Q platform into emergency medicine, specifically looking at NETosis. Another busy and exciting time ahead for sure, and I look forward to providing you with further updates throughout the year. With that, I'll pass back to Cameron Reynolds, our Group CEO. Cameron? Thanks, Tom, and thank you, Terig, for those updates. Great progress indeed. I'm delighted with the progress we have made with Nu.Q Vet, a fundamental part of the business with clear potential to generate significant revenue for the company. Our goal is to make canine cancer screening and monitoring accessible worldwide, and I'm delighted that we are moving ever closer to realizing our mission. I will wrap up the call today by updating you on another key product pillar, Nu.Q NET. Our team continues to work diligently to bring Nu.Q NET to market. Ee are now undertaking large-scale finding studies across multiple sites in the U.S. to determine clinical utility in sepsis and support our application to the FDA's Breakthrough Devices Program. We strongly believe the Nu.Q NET's test is a groundbreaking diagnostic aid that clinicians can use to detect the diseases associated with NETosis. Just last week, we held a webinar led by Dr. Andrew Retter, an intensive care consultant attending with extensive experience in managing sepsis in patients. The webinar was well-attended and focused on the burden of sepsis and challenges of treatment, the fundamental role NETosis plays in sepsis, and the need for a solution like Nu.Q NET. It's available to watch now on our website. As another highlight of the quarter, last month, we also sponsored a GenomeWeb webinar titled The Long Journey of EZH2 Inhibitors from Imperfect Tools to Precision Medicine. It was led by Dr. Francesco Crea, Director of Research at The Open University, and Dr. Francesca Celani, Medical Oncologist at the University of Pisa. The session focused on EZH2 inhibitors in cancer therapy and the development of non-invasive diagnostic tools. It also gave us the opportunity to show how Volition works effectively with organizations like The Open University through our innovative Nu.Q Discover program. The webinar was well-attended with a very engaged audience and representation across industry and academia. You can also watch it back on demand by visiting the GenomeWeb website. We've also made strong progress in both our Nu.Q® Cancer and Nu.Q® Capture pillars. I will update on those in the coming quarters. To sum up, I am very proud of the progress we are making as a team at Volition. After many years of developing and optimizing Nu.Q®, which we believe is a groundbreaking nucleosome quantification technology, we are now commercializing the platform and generating revenue. It is a hugely exciting time for us at the company and powered by Nu.Q®. We look forward to sharing further updates and milestones with you over the coming quarters. We also hope you will be able to join us for our Nu.Q Capital Markets Day event later Today, where we'll be joined by Dr. Andrew Retter, Professor Wilson-Robles and Dr. Sue Ettinger. In drawing this earnings call to a close, I'd like to thank you for joining us on the call today. We very much appreciate it. We're happy to take your questions. Operator. Thank you very much, sir. We will now be conducting a question and answer session. As a reminder, if you have a question, please press the star key followed by one on your touchtone phone. If you'd like to withdraw your question, please press the star key followed by two. Please note if you're using speaker equipment, please lift the handset before making your selections. The first question comes from Bruce Jackson of The Benchmark Company. Good morning. Thank you for taking my questions. On the vet side, I know that you sell the test to the vet labs and then the doctors order from there. Do you have any visibility or do they provide you with any insight into the ordering patterns of the physicians? Do you happen to have any indication as to the repeat ordering trends? Hi, Bruce. Good morning. Thanks for the question. We don't have any formal data coming back from them, but we're in contact with all of our partners on the use of the test, and it has been straight across the board. They're extremely excited about the reception that the veterinarians are utilizing our tests. We're in over 45 states in the United States right now, and they're thrilled with it. They're continuing to collect additional data and are gonna utilize that data for additional launching in the second half of 2023 as well. We really couldn't be more excited about the positive responses they're giving us when we inquire. Okay, great. Just a quick follow-up question on that. With the lab ordering trends to you, should we think about it as building in sort of a linear fashion here throughout the year, or could it potentially be a bit lumpy as the labs take in orders and then adjust according to the end user demand? Darren. Yeah. Let me take that one. It's a bit difficult to predict, but we do expect it to be a little bit lumpy at this point. We're not sure whether it will take off in a linear fashion exactly, because, you know, they will roll it out to different labs at different points in time. So you could see more of a step increase as we go through the year. Yeah, we don't have insight as to when those steps will occur, but we do expect it to increase, yeah, slowly over the year. All right. Of course, Bruce, there will also be when Heska start sales as well, that'll pick up through the back half of the year as well. We expect them both to be launching in a wide range of countries later this year as well. Yeah, absolutely a little lumpy at the start, but I think it'll pick up very strongly through the end of the year and through next year. That's it for me. Thank you very much. Thank you, Bruce. Have a great day. Thank you. The next question comes from Steven Ralston of Zacks. Good morning. Morning. Morning, Steven. Morning. First of all, your R&D line spiked up dramatically in the Q1 here. It was up 37% year-over-year and 24% sequentially. You alluded to that it was basically on this $1.1 million of increased R&D on the U.S. clinical trial activities. Could you give a little color behind that? Is that all Nu.Q NETs or are there other portions of that? In addition to that, in the broad R&D number, could you give us an idea if there's something else that's spiking up there that's going to give us a better idea on the progression of your other commercialization efforts? The increase over last year is mainly due to the clinical trial activities in the US, which is focused on NETs and in particular sepsis. That's the main driver. There is a little bit of increase in terms of our centers of excellence that we've been rolling out in Europe, again, focused on NETs in Europe, but the majority of it is driven by the increase in activity for the US clinical trials. Yeah, that will continue into Q2, but we don't expect to see expenditures increasing from here on. Q1 is always the biggest quarter for us, both in terms of expenses, in terms of cash flow. We, you know, Q2 will for certain be lower than Q1, particularly on the cash flow side, where we'd expect it to be more in line with last year, probably somewhere in the range of $2 million-$2.5 million on the cash flow rather than what we saw in Q1. I think, Steven, it's probably important just to do a general strategy on this as well. Obviously we're incredibly excited with Nu.Q Vet and the launches, where they're going really well for us, and it'll just continue to pick up, we think. We are spending quite heavily on Nu.Q NET. I think it's a very important product for us, and having a human product in the U.S. FDA approved would also be a fantastic outcome for the company. We are spending on that. But we're also spending some money on the background of epigenetics. We want to stay on the cutting edge of epigenetics, and I think that's exactly what we're doing. It's a fantastic and growing field. We have also been doing a bit of background work on the capture side and the human cancer, which you'll probably hear about later this year and next year. I think we're keeping a strategy going of really focusing on the revenue in Vet and then Net, but also keeping on the cutting edge of epigenetics. I think it's a fantastic package and what we'll keep doing. Thank you. I've been watching these webinars that you've been putting out, really appreciate it. I usually don't do this, but I'm gonna just comment on your Nu.Q NET Sepsis webinar. I can clearly say that within the last year, that's the best webinar I've seen. It was very informative. I appreciate that effort. Lastly, if you could talk about, in the last conference call for the quarter, fourth quarter, you mentioned that you would share a revenue update on the Heska pre-sales or the point of care. Are you prepared to do that now? Sorry, just the, I didn't quite catch the question. The Heska pre-sales. Oh, the Heska pre-sales. No, we're not able to provide an update at this point in time. We'll probably be able to provide on it the next quarter. All right. Thank you very much. Thanks for your kind words on the webinar. I'll pass it on to our communications team. It's something we're very careful to try to do, which because NETs, I think, is a fantastic opportunity, but something which is takes a little time to understand. We will continue to put resources into communication, and it's great to hear it's being appreciated. Thank you. Thank you. Ladies and gentlemen, just a further reminder, if you'd like ask a question, you're welcome to press star and then one. The next question comes from Ross Osborn of Cantor Fitzgerald. Hi, good morning, everyone, and congrats on the progress. Thank you. Starting off, can we walk through the IDEXX commercialization plan, and specifically outside of the United States. You know, what countries are they targeting? As a follow-up, how much of a focus is Asia for you guys now for Nu.Q Vet? I know you have the Sage partnership there, and obviously it's a huge market, but I think, you know, to this point, it hasn't really contributed material revenue. Yeah, thanks for the question, Ross. They're collecting a lot of data in preparation right now for launching in the second half of 2023. They're going to be going into Canada, U.K., E.U., and Australia. There is some consideration for Asia for IDEXX at that point in time because they have a pretty strong presence in Japan in particular. That is all on the docket for them in the second half of 2023. Repeat your second question again so I can address that for you. Yeah. Just any update with the SAGE partnership. Yeah. I think an initial rollout in maybe Singapore. I could be wrong there. You know, it's been commercial, I believe, for almost a year now. Just, you know, just curious kind of the level of uptake there and focus for the company. Yeah. The SAGE partnership has been very good. It's also really allowed us to be a launching pad for Asia presence, and we're getting a significant amount of interest and discussions right now with other reference labs in the region, both in Southeast Asia and in Asia. We're in active discussions with several of them at the present time. It's been a real nice access and exposure for us, and we're delighted with the continued inquiries we're having and the discussions we're currently having with other labs. Okay, great. Thank you for providing that clarity. I realize it's a lesser focus for the company, but any update on Discover? I think revenue is down a bit in the quarter. You know, just curious to hear, you know, if the level of resources devoted to generating Discover contracts and servicing that business and if it makes sense to do that longer term. Yeah. Good, very good question. Just to recap, Nu.Q Discover is other people using our technology. There was a big burst at the start of last year when we kind of opened it up and went through all the inbound inquiries and closed them. We're extremely happy to have that revenue this quarter last year, and it was very significant for us and really showed the great interest in our platform. Obviously, at the moment, Nu.Q Discover, although it's great to have other people using it, and we continue on, and there's a few contracts in the pipeline, the real focus and what could make us a very successful company in the short term is revenue coming in from Nu.Q Vet and Nu.Q NET. We are continuing on with it. It's not getting a lot of resources, but it is something we are continuing to do, and we will have more contracts. I think obviously given the terms of Nu.Q Vet and Nu.Q NET, that's could swamp anything Nu.Q Discover could do. We have had some great partnerships. We're extremely excited with the interest has been shown, and we are continuing to work on Nu.Q Discover, and there will be more contracts, but it's not our focus at the moment. Okay. Makes sense. Thank you for taking my questions. Thank you. Have a great day. Thank you. Ladies and gentlemen, just a final reminder. You can now ask a question. You're welcome to press star and then 1 to place yourself in the question queue. Ladies and gentlemen, Apologies, sir. Go. That's fine. Go on. Thank you. Ladies and gentlemen, with no further questions in the question queue, we have reached the end of the question and answer session. I would now like to turn the conference over to Cameron Reynolds for closing remarks. Thank you. Thank you, everyone. I really appreciate you listening in. It's an incredibly exciting time for us. On the Vet side, it's a real honor to be running a company that has a very wide range of products now in launch. We'll keep you updated on all of those. A further reminder, we have a webinar this afternoon. We're all here at the New York Stock Exchange today, and we've got some great key opinion leaders who are even more excited than us, I think, about the potential for our products. You'll be hearing from them and from us on other updates. Please either listen in live or they'll also be available after. Also the webinars we talked about over the last few weeks are also available, if you wanna listen to them if you've missed them already. I think they're very informative, as Steven pointed out, and really give a great background into our platform and how we're launching it and how we think we're gonna become very successful on the commercial side this year and next. Thank you very much for your time. I really appreciate it. Thank you. Thank you, sir. Ladies and gentlemen, that concludes today's conference. Thank you for attending. You may now disconnect your lines. Thank you, Judith. Have a great day.