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Table of Contents SECURITIES AND EXCHANGE COMMISSION Washington , DC 20549 UNITED STATES ( Mark One ) ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31 , 2020 OR TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 ( d ) OF THE SECURITIES EXCHANGE ACT OF 1934 Delaware ( State or Other Jurisdiction of Incorporation or Organization ) FORM 10 - K For the transition period from 75 Sidney Street , Cambridge , Massachusetts ( Address of Principal Executive Offices ) Large accelerated filer Non - accelerated filer to Voyager Therapeutics , Inc. ( Exact Name of Registrant as Specified in Its Charter ) Commission File Number : 001-37625 ( 857 ) 259-5340 ( Registrant's Telephone Number , Including Area Code ) 46-3003182 ( IRS Employer Identification No. ) 02139 ( Zip Code ) Securities registered pursuant to Section 12 ( b ) of the Act : Trading Symbol ( s ) VYGR Title of each class Name of each exchange on which registered Common Stock , $ 0.001 par value Nasdaq Global Select Market Indicate by check mark if the registrant is a well - known seasoned issuer , as defined in Rule 405 of the Securities Act . Yes Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15 ( d ) of the Act . Yes Indicate by check mark whether the registrant : ( 1 ) has filed all reports required to be filed by Section 13 or 15 ( d ) of the Securities Exchange Act of 1934 during the preceding 12 months ( or for such shorter period that the registrant was required to file such reports ) , and ( 2 ) has been subject to such filing requirements for the past 90 days . Yes No Indicate by check mark whether the registrant has submitted every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S - T ( § 232.405 of this chapter ) during the preceding 12 months ( or for such shorter period that the registrant was required to submit such files ) . Yes No Indicate by check mark whether the registrant is a large accelerated filer , an accelerated filer , a non - accelerated filer , a smaller reporting company , or an emerging growth company . See the definitions of " large accelerated filer , ” “ accelerated filer , " " smaller reporting company , ” and “ emerging growth company " in Rule 12b - 2 of the Exchange Act . No X No Accelerated filer Smaller reporting company Emerging growth company If an emerging growth company , indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13 ( a ) of the Exchange Act . Indicate by check mark whether the registrant has filed a report on and attestation to its management's assessment of the effectiveness of its internal control over financial reporting under Section 404 ( b ) of the Sarbanes - Oxley Act ( 15 U.S.C. 7262 ( b ) ) by the registered public accounting firm that prepared or issued its audit report . X Indicate by check mark whether the registrant is a shell company ( as defined in Rule 12b - 2 of the Act ) . Yes No X X The aggregate market value of Common Stock held by non - affiliates of the registrant computed by reference to the price of the registrant's Common Stock as of June 30 , 2020 , the last business day of the registrant's most recently completed second fiscal quarter , was approximately $ 291.7 million ( based on the last reported sale price on the Nasdaq Global Select Market as of such date ) . As of February 19 , 2021 , there were 37,653,805 shares of the registrant's common stock , par value $ 0.001 per share , outstanding . DOCUMENTS INCORPORATED BY REFERENCE Portions of the registrant's definitive Proxy Statement relating to its 2021 Annual Meeting of Stockholders are incorporated by reference into Part III of this Annual Report on Form 10 - K where indicated . Such Proxy Statement is expected to be filed with the U.S. Securities and Exchange Commission not later than 120 days after the end of the fiscal year to which this report relates .