Hello everyone, and welcome to the Xeris Q4 and full year 2023 financial results conference call and webcast. My name is Emily, and I'll be coordinating your call today. After the presentation, there will be the opportunity for you to ask any questions, which you can do so by pressing star followed by the number one on your telephone keypad. I'll now turn the call over to Allison Wey, Senior Vice President of Investor Relations. Please go ahead. Thank you, Emily. Good morning, and welcome to Xeris Biopharma's Q4 and full year 2023 financial results and conference call. This morning we issued two press releases, one on the company's financial results and the other on refinancing our debt facility with Hayfin Capital. Both can be found on our website. We're joined this morning by Paul Edick, Chairman and CEO, and Steve Pieper, our CFO. After our prepared remarks, we will open the lines for questions. Before we begin, I would like to remind you that this call will contain certain forward-looking statements concerning the company's future expectations, plans, prospects, and financial performance. Forward-looking statements are subject to risks and uncertainties that could cause actual results to differ materially from those forward-looking statements. For more information on such risks, please refer to our earnings press release and risk factors included in our SEC filings, including our quarterly report on Form 10-Q. Any forward-looking statements on this call represent our views only as of the date of this call and subject to applicable law. We disclaim any obligations to update such statements. I'll now turn the call over to Paul. Thanks, Allison. Good morning, everyone, and thank you for joining us today. Let me start by thanking everyone who contributed in some meaningful way to us delivering an outstanding year for the company, including the patients we serve, the healthcare providers we enable, and the dedicated Xeris team that executes at a very high level every day. 2023 was an exceptional year of performance and growth for Xeris, highlighted by our total revenue, which grew an impressive 49% from 2022 to $164 million in 2023, and ending 2023 with over $72 million in cash. This revenue growth, along with Xeris's strong cash position, continues to demonstrate the sustainability of the enterprise we're building. In 2023, we significantly advanced our once-weekly subcutaneous XeriSol levothyroxine program. We completed enrollment in our phase II clinical study and have made considerable progress on manufacturing and device development. Even more exciting, we're starting to demonstrate the potential value of our Xeris technology business. In 2023, we successfully advanced this business and generated over $10 million in total revenue. I'm going to focus the majority of my remarks on our full year performance, and Steve will touch base on the full year and Q4 performance and his prepared remarks, starting with our commercial business and starting with Gvoke. Gvoke had another outstanding year in 2023. We grew revenue by 28% to $67 million. We grew Gvoke prescriptions to over 215,000 in 2023, and Gvoke continues to outpace all other products in the category and drove 10% glucagon market growth in 2023. The new ready-to-use glucagon products now represent almost 80% of both new and total prescriptions, and Gvoke continues to capture market share. At the end of February, Gvoke's market share of new and total prescriptions in the retail glucagon market are approximately 34% and 32%, respectively. As I've said before, we see tremendous opportunity for Gvoke. We estimate that approximately 15 million people with diabetes are at increased risk of severe low blood sugar. A primary risk factor for a severe low is being on insulin and sulfonylurea, and those who are should be carrying ready-to-use rescue glucagons like Gvoke HypoPen. However, less than 10% of people at risk of a severe hypoglycemic event have a ready-to-use rescue glucagon product on hand, leaving far too many people with diabetes still left without protection against a potentially life-threatening severe low blood sugar event. We are just scratching the surface of this opportunity. The universe of healthcare stakeholders and advocates have declared that the addition of a ready-to-use rescue glucagon such as Gvoke should be a key element of the standards of care in diabetes. The challenge remains getting practicing healthcare professionals to adopt these standards of care as their standards of practice. As I mentioned previously, Gvoke is driving the majority of market growth in this category, and we believe that Gvoke will continue to be the primary and dominant voice in the market. On to RECORLEV. We're very pleased with our progress with RECORLEV, driving patient referrals and converting them to new patient starts. We see tremendous potential for RECORLEV in increasing dynamic Cushing's market. The key difference from most other products used in the category is that RECORLEV actually treats the underlying condition in Cushing's by normalizing cortisol levels in the body, which is a differentiation that resonates with physicians. We grew RECORLEV net revenues to $29.5 million, nearly a 300% increase compared to the prior year, and referrals and new patient starts have outpaced our expectations each quarter in 2023. RECORLEV generated $9.8 million in net revenue for the Q4, an increase of 158% over the same period in 2022, and an increase of 21% over the Q3 2023. We're very pleased with the steady increase in RECORLEV revenue quarter over quarter. Patient referrals continue to be robust, and the underlying patient demand grew 28% over the Q3. The number of unique prescribers with new referrals also continues to grow. The average number of patients on RECORLEV increased over 145% from the same period in 2022. Our healthy pipeline of patient referrals and healthcare professionals using RECORLEV as a first-line therapy are key indications that RECORLEV is seen as an important option for Cushing's patients, especially given RECORLEV's multi-pronged approach to suppressing cortisol production as post-surgery treatment for Cushing's syndrome. Moving to KEVEYIS. We grew KEVEYIS revenue 15% compared to 2022, despite the launch of a generic competitor in early 2023. This performance exceeded our expectations for the brand in 2023 by delivering $56.8 million, well in excess of the $40 million revenue milestone which triggered a CVR for Strongbridge shareholders. Steve will provide more detail on the CVR. In the Q4, revenue for KEVEYIS was $14.1 million, which is an 11% decrease from the Q3 of this year. However, it was a 2% increase compared to the same period in 2022. In the second half of the year, we started to see modest patient loss to generic competition. The Q4 was the Q1 we saw pressure from the generic impacting our net revenue. That said, even with a whole year of generic competition, we exited 2023 retaining over 90% of our patients on KEVEYIS. This is a testament to our team's ability to find new patients and the value of our Xeris Care Connections team, which provides support for primary periodic paralysis patients and providers. As a result, patients and medical community are willing to fight for the KEVEYIS brand. That said, we expect payer pressure will persist, and we may see sequential quarterly decline in KEVEYIS revenue in 2024, which we've accounted for in our 2024 guidance that we'll talk about later. However, we continue to find new patients and build the top of the referral funnel, which is key to maintaining KEVEYIS' contribution to our commercial portfolio. Before I move on to our levothyroxine program, a quick comment on the Change Healthcare cybersecurity issue 2 weeks ago. We believe this has the potential to temporarily slow adjudication of pharmaceutical prescriptions in general. The degree to which that potential for delayed adjudication may impact our specialty pharmacy and retail business is yet unclear and really too early to stop. Now on to our XeriSol levothyroxine program, the potential once-weekly subcutaneous injection. The last patient last visit was just last week, which keeps us on track for data from the phase II study mid-year. This oral liquid dose conversion data will help to inform our proposal to the FDA for a pivotal phase III program. We anticipate requesting an end-of-phase II meeting later this year. If we gain alignment with FDA on a phase III study program, we could start that study as early as mid-2025. Now on to our formulation technology business. We're very excited about the potential value this business can provide for patients, caregivers, healthcare professionals, and our Xeris partners. We made a lot of progress validating the Xeris technology in 2023, from signing the Regeneron platform deal a year ago to successfully formulating the pre-prescribed target product profile for XeriJect TEPEZZA, and as such, receiving the associated $6 million success payment from Amgen. As recently as January, Amgen executed the exclusive worldwide license agreement to develop, manufacture, and commercialize a subcutaneous formulation of TEPEZZA using our XeriJect technology in thyroid eye disease. Under terms of the agreement, Xeris has the potential to receive up to $75 million in development, regulatory, and sales-based milestones, as well as an escalating single-digit royalty based on future sales of TEPEZZA using the XeriJect technology. Next step in this program, a newly integrated Amgen team has been formed around the XeriJect program. Development work continues, and planning is underway in preparation for initial clinical stage activities. As for the Regeneron collaboration, we have completed formulation development for both initial molecules. Regeneron's stability and non-clinical evaluations will take place over the next six months. Assuming continued success, that could lead to their potentially executing a license option for further clinical development and commercialization of any of the molecules in the platform, which would trigger an additional one-time payment. Regeneron also has the option to nominate additional molecules for formulation development at any time, for which we would receive an additional upfront per molecule. We're excited about the potential for our XeriJect business and believe this could be a significant contributor to the growth of Xeris over time. We continue to discuss additional XeriJect collaborations with numerous companies. Before I go into our 2024 financial guidance, I want to touch on our debt refinance with Hayfin Capital that we announced this morning. Since we began our relationship with Hayfin two years ago, we have proven to them that we can execute on our strategy, growing and de-risking our enterprise. This has given them the confidence in Xeris to further support us by committing an additional $50 million at close of the transaction with another $15 million of committed capital at our discretion to settle the 2025 convertible notes and by providing $100 million of uncommitted capital for potential M&A purposes, while lowering our total cost of capital overall. Hayfin has been a great partner to Xeris, willing to support the growth of our enterprise with non-diluted capital. Steve will go into more details on the transaction. Looking at 2024, as our momentum continues, we expect to grow total revenue in the range of $170 to 200 million. Our total revenue range implies a 4% growth at the low end, 22% growth at the high end, and 13% at the midpoint. However, net of non-recurring partner revenue, our range for 2024 represents approximately a 10% growth at the low end, 30% at the high end, and 20% at the midpoint. Very positive potential continued growth of the enterprise either way you look at it. Recall in 2023, we initially gave a wide revenue range as we were not sure of the rate of expected decline in KEVEYIS due to generic competition and revenue contribution from technology partners, which is an episodic in nature altogether. Same unknowns and uncontrollables exist for 2024. That said, this double-digit revenue growth, coupled with our recent debt financing and continued disciplined cash management, allows us to further invest in the growth of our commercial products, fund phase III readiness activities for our pipeline levothyroxine program, and lastly, make incremental investments in our emerging technology business. We still expect to end 2024 with a very healthy cash position of between $55 and 75 million, further demonstrating the sustainability of the enterprise that we're building. I'm now going to turn the call over to Steve for additional details on our financial performance. Thanks, Paul, and good morning, everyone. As Paul mentioned, 2023 was another year of exceptional performance and growth for Xeris. All three of our commercial products grew revenue for the full year and Q4 compared to last year. We ended the year with net product revenue of $153.4 million, a 40% increase compared to last year. Our various partnerships contributed meaningful revenue with a record $10.5 million of other revenue for the full year 2023. Total revenue in 2023 was $163.9 million, a 49% increase compared to last year. Revenue growth, coupled with our disciplined cash management, resulted in Xeris ending 2023 with cash of $72.5 million and generating $6.5 million of cash in the Q4. This is a significant milestone for Xeris, and it continues to demonstrate our ability to be a self-sustaining enterprise. Moving on to our Q4 and full year results. For the Q4, total revenue was $44.4 million, representing a 34% increase over the same quarter last year. Gvoke net revenue for the quarter was $18.6 million, representing a 25% increase compared to the same period last year. Full year net revenue was $67 million, representing a 28% increase compared to last year. In the Q4, Gvoke prescriptions topped 59,000, a 43% increase compared to the same period last year. Consistent with the historical trend following the typical back-to-school spike for the glucagon market in Q3, the total glucagon prescription market declined 7% in the Q4. Despite the 7% market decline, Gvoke total prescriptions grew 1% in the same period, ending the quarter with total retail market share of approximately 31%. Gvoke continues to gain market share in 2024, ending February at approximately 32%. Moving to RECORLEV. RECORLEV net revenue was $9.8 million for the Q4 and $29.5 million for the full year 2023. Compared to Q3 2023, net revenue increased by 21%, driven by a steady increase in underlying patient demand. We are encouraged by the growth in RECORLEV's patient demand, which has been fueled by a consistently healthy pipeline of referrals. Moving to KEVEYIS. KEVEYIS net revenue for the quarter was $14.1 million, representing a 2% increase compared to the same period last year. Full year 2023 net revenue was $56.8 million, representing a 15% increase compared to last year. While our strategy to invest in KEVEYIS and defend brand prescribing has been successful to date, in Q4, we saw a slight decrease in patient demand due to increased generic pressure. We will continue to deploy strategies to protect KEVEYIS, and we'll continue to invest in Xeris Care Connections as they offer the best-in-class therapy and support for primary periodic paralysis patients. Before I move on to our other revenue, and as I covered in my prepared remarks in November, I want to again address the KEVEYIS CVR milestone that was achieved in 2023. 2023 KEVEYIS net revenue was over $56 million, exceeding the KEVEYIS CVR milestone of $40 million. Consistent with my previous remarks, we will settle this obligation in Xeris common shares later this month and anticipate issuing approximately 7.5 million common shares, which is a modest increase of approximately 5% of outstanding shares. Moving on to our other revenue, in 2023, we generated $10.5 million in other revenue. This was mainly comprised of our technology partnership business, which we significantly advanced in 2023. We will be making incremental investments in our technology business in 2024 to further advance our existing partnerships and attract new partners in 2024 and beyond. These investments include accelerating GMP manufacturing readiness and clinical scale-up to enable our partner programs to move into clinical development. We believe these investments are necessary to further demonstrate the full value of our technology platform. Looking ahead to 2024, we expect to grow total revenue in our issuing full year total revenue guidance of $170 to 200 million. 2024 revenue will be driven by the continued growth of Gvoke and RECORLEV and impacted by an expected decline in KEVEYIS and the potential episodic contributions from our technology partnership business. Moving down the P&L, cost of goods sold in the Q4 was $7.6 million, a 20% increase compared to the same quarter last year. For the year, cost of goods sold was $28.6 million, an increase of 27% compared to last year. These increases are mainly driven by higher product sales. Research and development expenses were $6.4 million for the quarter and $22.3 million for the full year, a modest increase of 7% compared to prior year, driven by our levo phase II clinical study and an increase in personnel costs. Selling general and administrative expenses were $37.6 million for the quarter, an increase of $3.2 million relative to the same period last year. This increase was driven by rent expenses related to the facility lease that commenced in April 2023 and personnel costs primarily driven by a modest field expansion. Compared to last quarter, SG&A was relatively flat. On a full year basis, SG&A was $146.1 million, an increase of approximately $8 million or 6% versus last year. Moving on to cash, we ended the year with a very healthy cash position and generated positive cash for the first time in Xeris's history in the Q4. As of 31 December, 2023, we had total cash of $72.5 million compared to $66 million as of 30 September, 2023, generating $6.5 million in cash in the quarter. Cash utilization for the full year 2023 was $49.5 million, a significant improvement over 2022 cash utilization of over $100 million. Earlier today, we announced that we refinanced our senior secured term loan with Hayfin Capital. As a result, we are reducing the interest rate we pay on our loan by over 200 basis points as we move from a SOFR plus 9% rate to a SOFR plus 6.95% rate in the new agreement. Additionally, we drew down an incremental $50 million at close, resulting in a total facility of $200 million, with the ability to draw down an additional $15.2 million to redeem our outstanding 2025 convertible notes. The new loan is interest-only with a term of five years. We must maintain minimum cash and achieve minimum revenue targets. These covenants are in line with our previous Hayfin agreement. This new agreement is a testament to the confidence Hayfin has in Xeris's ability to successfully execute our strategy. From a cash guidance perspective, we expect to end 2024 with a very healthy cash position of $55 to 75 million, which includes the incremental $50 million from Hayfin, less one-time costs including a call premium, commitment fees, and other advisor and legal fees, adding a net $35 million to cash in the Q1. We expect SG&A to be relatively flat to 2023. Furthermore, we expect R&D to increase by approximately $5 million relative to 2023 as we make strategic investments in our own pipeline and our emerging technology partnership business. The incremental capital from our refinanced Hayfin facility, coupled with the continued growth of our revenue, allows us to further invest in the growth of our commercial products, fund phase three readiness activities for our own pipeline levo program, and lastly, make incremental investments in our emerging technology partnership business. To summarize, Xeris had a year of exceptional performance and growth in 2023, and we look forward to continuing to build on that momentum in 2024. With that, operator, please open the line for questions. Thank you. As a reminder, if you would like to ask a question today, please do so now by pressing Start, followed by the number one on your telephone keypad. If you change your mind and would like to be removed from the queue, you can press Start and then two. Our first question today comes from Oren Livnat with H.C. Wainwright. Please go ahead. Thanks. I have a couple. Just to get out of the way, on the Amgen partnership, first, congrats on further validation of that platform. Beyond what you had in the script, is there anything you can tell us about the expected timelines to the next important value-creating event and when we might start to get some more clarity on that program? And to see if you are the only iron in the fire they have now on sub-Q TEPEZZA, so to speak, or is it, within your contract, are they allowed to also be continuing to work with other tech platforms? And I have a follow-up. Thanks. I'll take the second one first. Oren, good morning. Welcome. They can work on anything they want to work on. We don't have an exclusive deal. They've already announced, or even Halozyme announced that they were no longer working on their program. They've got some internal programs, and you know, I believe that Amgen may have an internal program also. So if I was in that market with a multi-billion dollar asset, I'd have a lot of a lot of irons in the fire. We're one of those. And with our technology, I believe probably the best option that they have to extend that franchise and grow that franchise as a patient self-administered drug. And the second part, timing to an event. As you can imagine, the integration of the companies is just completing, and the team around TEPEZZA has been reformed, and they're getting up to speed. The work we were doing in terms of preclinical is still ongoing, and they're mapping out their development and clinical program. Things are going along well, you know, with a little bit of a disruption between the Horizon and then Amgen transition. All right. Thanks. And, on levo, you told us maybe in January that you completed enrollment in the last visit, right? Can you give us, I guess, any more granularity on timing other than midyear, or I guess probably not. But importantly, in the interim, have you had any informal discussions with the FDA or perhaps, more work with your consultants that gives you any more color and expectations around potential phase III in, the requirements with regards to endpoints? Yeah. So in January, we said we had completed enrollment, and we just last two weeks ago or last week completed our last patient last visit. It'll take a few months to analyze all that data that's been collected, so that's why we, you know, we should have data midyear. We will, as fast as we can, go to the FDA for a, you know, end of phase two, phase three discussion. That has its own calendarization. That'll take us pretty much to the end of the year, we believe. And with good alignment on what a phase three program might look like and to the other part of your question, we don't know, and we haven't had conversations with them about a phase three program yet. Our going-in assumption is one study. in that, if we get good alignment by the end of the year, we can start that study. We can get going on IRBs and all that kind of stuff and get that study up and running, best case middle of 2025. I think I covered the whole thing. I'll jump back into the queue. I appreciate it. Thanks. The next question comes from Glen Santangelo with Jefferies. Please go ahead, Glen. Yeah. Good morning. Thanks for taking my questions. Hey, Paul, just a couple of product questions for you, and then I have a follow-up for Steve. You know, first, you know, you're two growth markets here. When you think of Gvoke, I mean, Amphastar now owns Baqsimi for a couple few quarters. And then as it relates to Cushing's, you know, Teva recently launched a generic version of Korlym. So I'm kind of curious to get your take, you know, how you see the competitive landscape in each of those markets kind of shifting, and, you know, are those shifts positive for you, or are they negative? Thanks, Glen. Those are important questions. So, Gvoke and Amphastar, we want them to be as active as possible in the marketplace. That's the only way right now. Like I said in my prepared remarks, there's about 10% growth in the market. We're basically driving all that growth. We think that Amphastar, kind of picking up the ball from Lilly and really getting going with their commercial business, is only going to fuel market growth, and that's good for us. We've never really, even with Lilly, we weren't ever really selling Baqsimi against Gvoke or Gvoke against Baqsimi. We're both selling for the benefit of the patient. So, the opportunity is so huge. Market growth is really what both companies should be focused on. It's what our focus is, and we're hopeful that Amphastar really gets going in a more significant way. As for Teva and the dynamic in the Cushing's market, as we know, the Cushing's market has been generic for a long time with several new big brands over the last decade or so. There's always been that dynamic. I think this particular situation with Korlym being as big as it is, that dynamic, we believe, will play in our favor because we think we have a really good differentiation versus Korlym in terms of our ability to normalize cortisol. And, having it generic in the market is going to sort of be disruptive for that franchise and, to our estimation, kind of put it in play for others like us to take share. So, I see both dynamics as potentially positive for us. Okay. Well, thanks for that. And maybe if I could just follow up with Steve on the guidance. Steve, in you know, in your prepared remarks, you sort of gave us a little bit of color around the guidance, but you know, when we think about the growth, 4% to 22%, it's a pretty big range. And so I was wondering if you could just you know, unpack that a little bit. Are there any sort of incremental sort of milestone payments you're expecting within those within that guidance range? And then secondly, you know, when you think about your three products, it kind of sounds like you're suggesting, you know, KEVEYIS is seeing some weakness, and so maybe we should expect that to be down modestly in 2024 with that offset by growth in the other two products. Am I thinking about all that correctly, or is there anything more you can give us related to the guidance? Well, I think we might need to tag team that one a little bit. So I'll take the various products. KEVEYIS, I mean, we had an amazing 2023 with KEVEYIS. We've said all along, sooner or later, we're going to start losing a few patients. Sooner or later, we're going to see some price liquidation. The degree to which that is going to potentially happen is the potential downside is just as big this year as it was last year. And our guidance was to reflect a wide range because we weren't sure. And so what we see so far this year is a little bit of patient loss, but we're not too sure of the degree to which that's going to accelerate or not. I'll turn it over to Steve. Yeah. Yeah. And I think, you know, we were—I think we were hopefully pretty clear in our prepared remarks that we do expect a decline, as opposed to 2023 where we saw growth. So yeah, that's driving the wide range. I think we're excited about, you know, the growth, the continued growth of both Gvoke and RECORLEV. On the top end of the guidance, yeah, I think that, you know, we touched a little bit on the kind of episodic nature of this technology partnership business and the contributions. We saw $10.5 million from our various partnerships in 2023. The degree to which that is sticky again in 2024 remains to be seen. We don't control that fully, as you know. That is largely at the discretion of our partners. So, you know. The pace of our partners. The pace of our partners. So yeah, that I think you're thinking about it the right way, Glen, that, you know, that's, you know, what's driving the wide range in 2024. And the potential lack of growth in KEVEYIS, we expect to be made up by Gvoke and RECORLEV. And that's why we also in my remarks, I gave a little bit of the range. If you took out the non-recurring one-timers, the range is greater growth. I mean, all double-digit growth across the range, so. Thanks for the details. Sure. Our next question comes from Chase Knickerbocker with Craig-Hallum Capital Group. Please go ahead. Good morning, guys. Yeah, congrats on the good finish to 2023. Maybe just to start on a clarifying question on guidance. So ending the year, obviously, with $72.5 million in cash, based on that first press release, you're adding about $35 million in the Q1. And so is my is my math right that that means, you know, cash burn if we kind of take that $107.5 million, you know, cash number combined is somewhere around $40 million at the midpoint of your cash guide? Is that kind of the right math there? Yeah. You're about right. Got it. Thanks for that. You know, maybe just first starting with KEVEYIS, what actions are the payers taking? Just a little bit more detail there as far as what you've seen so far. Are they, you know, forcing patients to switch that are currently on therapy, or, you know, when you're getting them to the top of the funnel, they're pushing them to the generic first? Just kind of clarification there on exactly what's happening. And then if we look at 2024, is it mainly going to be volume is what you're expecting, or do you expect to give some ground on price as well? We don't expect any more movement on price unless there's a second generic at the end of the day. It's going to be volume. Payers are going to do what the payers do. I mean, it's all the same stuff. There's a denial. There's an appeal, etc. Little by little, they cleave off a few patients here and there. It's in their best interest. We get that. And they're going to. We believe that's going to persist, and that will result in more patient loss, depending net, net, depending on how fast we fill the funnel. You know, there's still a lot of patients out there. We're going to be still very aggressive. But we have to be forward-looking in terms of our expectations for decline. So that's what we're signaling. I think that. Yep. That answers it. Thanks. And then on RECORLEV. You know, kind of first, just kind of give us a little bit of a look into the background as far as, you know, how's the funnel kind of looking? Are you seeing any sort of, you know, shrinkage in kind of time from, you know, script written to script finally being filled, and then any kind of increase in your success rate of, of kind of, you know, appeals and all that, just, you know, success rate of going from, you know, script written to script filled? Yeah. So we're thrilled with the continued growth in the referrals to therapy. I mean, it is really accelerating. We're thrilled with the amount of patients that are being referred to therapy. Our conversion to patients on drug continues to be really solid and continues to grow, so we're happy with that. The time factor is real. I mean, the more you grow, the more patients you put on, the more you become a target with payers, and it takes more time. That being said, and I've said this before, if you look at the retail market for Gvoke and you say, "What would be a good percent of covered lives between commercial and Medicare?" You know, 75% would be great. 80% is about as good as you get in the pharmaceutical business. In rare disease and these expensive drugs, 50% to 60% rate of conversion from referral to patients on drug, we think, is equivalent and really good. And it varies in that range, you know, sometimes it's a little slower. Sometimes it's a little more. But it's in that 50% to 60% range. And we think that's a solid conversion percentage for the number of referrals we're getting. And then kind of taking that commentary and kind of relating it to what 2024 might look like, I mean, this is kind of a hard one for us to model. Obviously, it's been a little bit lumpy, as far as growth goes. I mean, what should we think of as far as, like, a sequential growth rate? Should we think of it as kind of, you know, bouncing between the low teens we saw in Q3 of 2023 and kind of the low 20s that we saw in Q4 of 2023, you know, as it relates to kind of how the funnel's looking and how those kind of conversions have been trending? Yeah. I think good question, Chase. And, you know, we haven't. We've been pretty deliberate not providing specific product guidance. But what I would say is I think you can expect kind of a similar steady increase in patient demand and revenue growth over 2023. So, I don't think that there is. We're not expecting some kind of stepped function increase, you know, in the middle of the year, that would accelerate that. At least that's not, you know, in the cards right now. But, I think to expect a similar kind of steady growth, year-over-year, is a fair kind of starting assumption. Yeah. Great. Thanks for the time, guys. Thanks, Chase. The next question comes from Roanna Ruiz with Leerink Partners. Please go ahead. Great morning, everyone. So, question for XP-8121. Could you remind us what your expectations are for the phase two data coming this year, and what kind of results would you hope to see that would give you more confidence to advance into phase three? Hey, Roanna. Good morning. This study is predicated on the confirmation of the conversion from the oral dose to the liquid dose at more dosage strengths across the range. So Levothyroxine has, like, 10 or 12 different dosage strengths. And our phase I study, where we provided the FDA with a couple of those, you know, a couple dosage points, they just wanted to see it across more dosages and with, you know, patients who are actually on levo or former levo patients. So the information we will get will be a confirmation of that conversion at every dosage across the range, number one. Number two, we're gathering a great deal of information on the market need relative to the screen failures we've seen. Our goal was to get patients who were stable on current medication, and they were hard to find. So that will be important data as well. But it's just a confirmatory study for the dosage conversion. And then we'll have a discussion with the FDA on phase III program. Got it. Super helpful. And, for RECORLEV too, what are you guys hearing anecdotally from the field force in terms of their interactions with physicians about its profile? And, what are you thinking about its expected steady growth into 2024? Just like broad strokes, could it come from the field force, physicians getting more educated or more experience with RECORLEV, something like that? Thanks, Roanna. The patients are coming from everywhere. The more physicians are getting exposed to RECORLEV, the more it becomes a valuable tool for them. So, you know, we've seen individual physicians go from trying it to using it first line. So it's the experience that they get, which patients are being cortisol is being managed and normalized. Patients are not having a lot of side effects. Physicians get more and more comfortable. In terms of the physician interaction in the field, it's been very receptive. We're getting, you know, great conversations with physicians. The receptivity to RECORLEV has been very high. So that's been very positive. I mean, depending on you know, if you go do doctor calls, you're going to find ones that have never even heard of RECORLEV because they're not accessible to us. But the vast majority of physicians that are accessible, initial trial has been good, a broad cross-section of physicians, and the experience has been positive. So that's all. I think that's all good. Got it. Thanks. The last question comes from David Amsellem with Piper Sandler. Please go ahead. Hey, thanks. So on RECORLEV, I'm sure you guys are well aware of the Corcept study, called Catalyst, which looked at is looking at prevalence. And that's going to be presented later this year at ADA. I guess I wanted to just get your general thoughts on how you're thinking about those results in terms of the prevalence of hypercortisolism, what you think that could mean for RECORLEV and the opportunity for the product going forward. And, you know, to the extent that there is indeed a fundamentally different understanding of hypercortisolism, do you envision expanding your commercial organization to target a wider audience of physicians, namely diabetologists? How are you thinking about all that? Thank you. Okay. There's a lot to unpack in there, David. Bottom line, we like the direction that Corcept is going in with the Korlym franchise because we do believe that moving up in terms of patient severity is a good thing. Market expansion is really, I believe, their goal, which is good for us as well. We will benefit from that market expansion. And if you recall, I think the last call, we talked about we originally were targeting 3,200 more severe patients. And now our target is expanded to about a patient base of potentially 8,000. And I think the strategy of moving up in the treatment paradigm, it's even bigger than that. So that's important for us. I mean, as they drive market growth, that expansion helps us as well, so. Okay. That's, that's helpful. And then in terms of expanding the commercial infrastructure? We always look to add resources wherever we can and, you know, however when we can afford it. One of the things, as Steve said, the benefit of having a great partner like Hayfin is they recognize the progress we've made and the degree to which we've de-risked the business. They want to see us invest further for additional market penetration in our commercial business. They want to see us advance the technology business. And they want to see us advance levo. So, you know, they've really stepped up at reduced cost to help us do all of the above. We aren't expanding tomorrow in the commercial organization, but we're always looking at it. You know, this will be an important year from that perspective. Okay. That's helpful. And then, sorry if I missed this, but are you getting frontline Cushing's patients onto RECORLEV? Is that a decent chunk of the overall patient mix thus far? Today, it's a—it's a pretty good chunk of the overall patient mix. The answer that is yes, we are getting them. Those patients take a little bit longer to adjudicate insurance, but we're being very successful there as well. Early on, we were getting only the patients who were switching. But as physicians get comfort with a patient that has been on a couple of different things and has tried several different drugs and RECORLEV answers his, his need, then we begin to get first-line patients from that clinician. So, Okay. Thanks. I'll leave it there. I'll now turn the call back to Paul Edick for closing remarks. Thanks, everybody, for great questions. Thanks for listening today. As you heard, we have delivered another year of exceptional growth, and we're very proud of our performance to date. We expect that momentum will continue in 2024. We look forward to another year of growing an enterprise for which we can all be proud. Thank you very much. Thank you, everyone, for joining us today. This concludes our call, and you may now disconnect your lines.